FANCM and CENPX

Number of citations of the paper that reports this interaction (PubMedID 20347428)
108

Data Source:
BioGRID (pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down)

		FANCM	CENPX
Description		FA complementation group M	centromere protein X
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GO Annotations	Cellular Component	Nucleoplasm Fanconi Anaemia Nuclear Complex FANCM-MHF Complex	Condensed Chromosome Kinetochore Nucleoplasm Fanconi Anaemia Nuclear Complex FANCM-MHF Complex
	Molecular Function	Four-way Junction DNA Binding Chromatin Binding RNA Helicase Activity Nuclease Activity Protein Binding ATP Binding Four-way Junction Helicase Activity 3'-5' DNA Helicase Activity	DNA Binding Double-stranded DNA Binding Protein Binding
	Biological Process	Resolution Of Meiotic Recombination Intermediates Replication Fork Processing DNA Duplex Unwinding Interstrand Cross-link Repair Double-strand Break Repair Via Synthesis-dependent Strand Annealing Replication Fork Reversal Nucleic Acid Phosphodiester Bond Hydrolysis Positive Regulation Of Protein Monoubiquitination	Resolution Of Meiotic Recombination Intermediates Replication Fork Processing Positive Regulation Of Protein Ubiquitination CENP-A Containing Nucleosome Assembly Interstrand Cross-link Repair Cell Division Kinetochore Assembly
Pathways		Fanconi Anemia Pathway	Deposition of new CENPA-containing nucleosomes at the centromere Fanconi Anemia Pathway
Drugs
Diseases		Fanconi anemia
GWAS		Metabolite levels ( 23823483) Severe influenza A (H1N1) infection ( 26379185)
Interacting Genes		10 interacting genes: APP CENPX ECT2 EME2 FAAP24 LRRK2 RMI1 RMI2 TRIM27 UBE2I	7 interacting genes: CENPS FANCM NKX3-1 REL TP53 TRIM54 UBE2I
Entrez ID		57697	201254
HPRD ID		13876	18121
Ensembl ID		ENSG00000187790	ENSG00000169689
Uniprot IDs		Q8IYD8	A8MT69 J3QRS1
PDB IDs		4BXO 4DAY 4DRB 4E45 4M6W	4DRA 4DRB 4E44 4E45 4NDY 4NE1 4NE3 4NE5 4NE6
Enriched GO Terms of Interacting Partners?
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