LRRC4C and CREB3L4

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		LRRC4C	CREB3L4
Description		leucine rich repeat containing 4C	cAMP responsive element binding protein 3 like 4
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Membrane Integral Component Of Membrane Cell Junction Schaffer Collateral - CA1 Synapse Glutamatergic Synapse Integral Component Of Postsynaptic Density Membrane	Golgi Membrane Nuclear Chromatin Nucleoplasm Mitochondrion Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Integral Component Of Membrane Nuclear Membrane
	Molecular Function	Protein Binding Cell Adhesion Molecule Binding Cell-cell Adhesion Mediator Activity	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific CAMP Response Element Binding
	Biological Process	Regulation Of Axonogenesis Modulation Of Chemical Synaptic Transmission Synaptic Membrane Adhesion	Spermatogenesis Endoplasmic Reticulum Unfolded Protein Response Positive Regulation Of Transcription By RNA Polymerase II
Pathways			CREB3 factors activate genes
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Cerebellum cortex volume ( 31530798) Cerebrospinal fluid beta-site APP cleaving enzyme levels ( 29751835) Cerebrospinal fluid p-tau levels ( 29274321) Diastolic blood pressure response to thiazide and thiazide-like diuretics in hypertension ( 31754133) Emphysema annual change measurement in smokers (adjusted lung density) ( 31324189) General risk tolerance (MTAG) ( 30643258) Iris color (L* coordinate) ( 30895295) Mosquito bite size ( 28199695) Myopia ( 27182965) Osteoporosis-related phenotypes ( 20548944) Post bronchodilator FEV1 ( 26634245) Post bronchodilator FEV1/FVC ratio ( 26634245) Risk-taking tendency (4-domain principal component model) ( 30643258) Smoking status (ever vs never smokers) ( 30643258) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Survival in colorectal cancer ( 26586795) Temperament (bipolar disorder) ( 22365631)	Age at first birth ( 27798627) Blood protein levels ( 30072576 29875488) Empathy quotient ( 29527006) Itch intensity from mosquito bite adjusted by bite size ( 28199695)
Interacting Genes		3 interacting genes: CREB3L4 NTNG1 WHRN	4 interacting genes: GANAB LRRC4C SLC19A3 SOX9
Entrez ID		57689	148327
HPRD ID		12303	06323
Ensembl ID		ENSG00000148948	ENSG00000143578
Uniprot IDs		Q4JIV9 Q4JIW0 Q9HCJ2	Q8TEY5
PDB IDs		3ZYJ
Enriched GO Terms of Interacting Partners?
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