QSOX1 and BEGAIN

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		QSOX1	BEGAIN
Description		quiescin sulfhydryl oxidase 1	brain enriched guanylate kinase associated
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Extracellular Region Extracellular Space Cell Endoplasmic Reticulum Lumen Golgi Apparatus Integral Component Of Golgi Membrane Platelet Alpha Granule Lumen Specific Granule Lumen Intracellular Membrane-bounded Organelle Intercellular Bridge Extracellular Exosome Tertiary Granule Lumen	Cytoplasm Membrane Synapse
	Molecular Function	Protein Disulfide Isomerase Activity Flavin-linked Sulfhydryl Oxidase Activity FAD Binding	Protein Binding
	Biological Process	Platelet Degranulation Protein Folding Negative Regulation Of Macroautophagy Neutrophil Degranulation Post-translational Protein Modification Cellular Protein Metabolic Process Cell Redox Homeostasis Oxidation-reduction Process Extracellular Matrix Assembly	Regulation Of Postsynaptic Neurotransmitter Receptor Activity
Pathways		Platelet degranulation Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Neutrophil degranulation Post-translational protein phosphorylation	Neurexins and neuroligins
Drugs
Diseases
GWAS		Anorexia nervosa ( 23568457) Blood protein levels ( 30072576 29875488) Pulse pressure ( 30224653 30578418)	Chronotype ( 30696823) Menarche (age at onset) ( 21102462) Metabolite levels ( 23823483)
Interacting Genes		3 interacting genes: BEGAIN UBE2D2 UBQLN4	24 interacting genes: ABLIM1 APP ATPAF2 BAHD1 CATSPER1 DEF6 DLG1 DLG4 DTNB ENKD1 FAM107A GFI1B HGS HID1 KIAA0408 QSOX1 RBL1 RIBC2 TRIM27 USP2 ZFP64 ZNF250 ZNF417 ZNF774
Entrez ID		5768	57596
HPRD ID		06785	06459
Ensembl ID		ENSG00000116260	ENSG00000183092
Uniprot IDs		A0A140VKE5 O00391 Q13876	Q9BUH8
PDB IDs		3LLI 3LLK 3Q6O 4IJ3
Enriched GO Terms of Interacting Partners?
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