VPS18 and HOOK1

Number of citations of the paper that reports this interaction (PubMedID 18799622)
41

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo)

		VPS18	HOOK1
Description		VPS18 core subunit of CORVET and HOPS complexes	hook microtubule tethering protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Lysosome Lysosomal Membrane Endosome Early Endosome Late Endosome Autophagosome Actin Filament AP-3 Adaptor Complex Clathrin-coated Vesicle HOPS Complex Late Endosome Membrane CORVET Complex Presynapse Glutamatergic Synapse	Cytoplasm Centrosome Cytosol Microtubule HOPS Complex FHF Complex
	Molecular Function	Actin Binding Protein Binding Syntaxin Binding Protein Binding, Bridging Metal Ion Binding	Actin Binding Protein Binding Microtubule Binding Identical Protein Binding Dynein Light Intermediate Chain Binding
	Biological Process	Intracellular Protein Transport Vesicle Docking Involved In Exocytosis Autophagy Endosome Organization Vacuole Organization Lysosome Organization Endosome To Lysosome Transport Regulation Of SNARE Complex Assembly Viral Entry Into Host Cell Regulation Of Synaptic Vesicle Exocytosis	Golgi Organization Endosome Organization Lysosome Organization Multicellular Organism Development Endosome To Lysosome Transport Protein Transport Cytoskeleton-dependent Intracellular Transport Cytoplasmic Microtubule Organization Early Endosome To Late Endosome Transport Manchette Assembly
Pathways
Drugs
Diseases
GWAS		Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)	Alcoholic chronic pancreatitis ( 28754779) Metabolite levels ( 23823483) Night sleep phenotypes ( 27126917)
Interacting Genes		20 interacting genes: AKTIP COPB1 EP300 GGA1 GGA2 GGA3 HOOK1 MON1B RAB7A RILP STX1A STX6 STX7 STX8 UBE2D2 UVRAG VPS11 VPS16 VPS33A VPS45	22 interacting genes: AKTIP ANK3 CDC5L CDK4 ERI3 FAM160A2 HOOK2 HOOK3 LMO2 MRPL37 MYSM1 S100A7 SYCE1 TBC1D7 TFIP11 USP2 VPS16 VPS18 VPS39 VPS41 ZNF250 ZNF785
Entrez ID		57617	51361
HPRD ID		09776	07428
Ensembl ID		ENSG00000104142	ENSG00000134709
Uniprot IDs		A0A024R9R3 Q9P253	Q9UJC3
PDB IDs
Enriched GO Terms of Interacting Partners?
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