PDZD4 and APIP

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

		PDZD4	APIP
Description		PDZ domain containing 4	APAF1 interacting protein
Image		No pdb structure
GO Annotations	Cellular Component	Cell Cortex	Cytoplasm Cytosol
	Molecular Function		Protein Binding Zinc Ion Binding Identical Protein Binding Methylthioribulose 1-phosphate Dehydratase Activity
	Biological Process		Apoptotic Process L-methionine Salvage From S-adenosylmethionine L-methionine Salvage From Methylthioadenosine Negative Regulation Of Apoptotic Process Protein Homotetramerization Pyroptosis Regulation Of ERK1 And ERK2 Cascade
Pathways			Formation of apoptosome Methionine salvage pathway Regulation of the apoptosome activity
Drugs
Diseases
GWAS			Chronic obstructive pulmonary disease-related biomarkers ( 23144326) Cystic fibrosis severity ( 21602797) Gamma glutamyl transferase levels ( 29403010) Lung disease severity in cystic fibrosis ( 26417704) Prostate-specific antigen levels ( 28139693) Systemic lupus erythematosus ( 19838195)
Interacting Genes		3 interacting genes: APIP APP GFI1B	17 interacting genes: APAF1 CFAP206 IMPDH2 LNX1 NIF3L1 NTAQ1 NUDT18 PDZD4 PPP1CC PSMA1 SDCBP SKP1 TNPO2 TSC22D4 VIM VPS25 ZBTB25
Entrez ID		57595	51074
HPRD ID		06601	14725
Ensembl ID		ENSG00000067840	ENSG00000149089
Uniprot IDs		B3KVR9 B3KW03 D3DWW0 Q17RL8 Q76G19	Q96GX9
PDB IDs			4M6R
Enriched GO Terms of Interacting Partners?
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