LRRC7 and NQO2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		LRRC7	NQO2
Description		leucine rich repeat containing 7	N-ribosyldihydronicotinamide:quinone reductase 2
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Nucleoplasm Centrosome Cytosol Plasma Membrane Cell-cell Junction Adherens Junction Ionotropic Glutamate Receptor Complex Postsynaptic Density Basolateral Plasma Membrane Cell Junction Specific Granule Lumen Neuron Projection Axon Initial Segment Synapse Postsynaptic Membrane Synaptic Membrane	Nucleoplasm Cytosol Extracellular Exosome
	Molecular Function	Protein Binding	Dihydronicotinamide Riboside Quinone Reductase Activity NAD(P)H Dehydrogenase (quinone) Activity Protein Binding Zinc Ion Binding Electron Transfer Activity Oxidoreductase Activity Oxidoreductase Activity, Acting On Other Nitrogenous Compounds As Donors Chloride Ion Binding Protein Homodimerization Activity FAD Binding Melatonin Binding Resveratrol Binding
	Biological Process	MAPK Cascade Embryo Development Positive Regulation Of Neuron Projection Development Receptor Clustering Neutrophil Degranulation Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Receptor Localization To Synapse Cell-cell Adhesion Neurotransmitter Receptor Transport, Endosome To Postsynaptic Membrane Neurotransmitter Receptor Transport Postsynaptic Membrane To Endosome Regulation Of NMDA Receptor Activity	Xenobiotic Metabolic Process Memory Electron Transport Chain Positive Regulation Of Neuron Apoptotic Process Oxidation-reduction Process Positive Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Vascular Smooth Muscle Cell Proliferation Positive Regulation Of Reactive Oxygen Species Metabolic Process
Pathways			Phase I - Functionalization of compounds
Drugs			NADH Menadione Melatonin Primaquine Resveratrol Flavin adenine dinucleotide 10-Propargyl-5,8-Dideazafolic Acid Quercetin Tretazicar (3S)-3-hydroxy-1-methyl-2,3-dihydro-1H-indole-5,6-dione N-[2-(2-iodo-5-methoxy-1H-indol-3-yl)ethyl]acetamide 5,8-dimethoxy-1,4-dimethylquinolin-2(1H)-one 6-methoxy-9-methyl[1,3]dioxolo[4,5-h]quinolin-8(9H)-one
Diseases
GWAS		Adventurousness ( 30643258) Attention deficit hyperactivity disorder ( 21784300) Body mass index ( 24348519) Cognitive decline rate in late mild cognitive impairment ( 26252872) Hypertension risk in short sleep duration ( 22322875) Obesity-related traits ( 23251661) Orofacial clefts ( 22419666) Psoriasis ( 25939698) Type 2 diabetes ( 31049640)	Blood protein levels ( 30072576 29875488) Urinary metabolite levels in chronic kidney disease ( 31959995)
Interacting Genes		11 interacting genes: ACTN2 ACTN4 ADGRB1 CAMK2A CAMK2G CDH2 CNKSR2 CTNND2 HOMEZ NQO2 TOR1A	5 interacting genes: DGCR6 GORASP2 IL32 LRRC7 MTCH1
Entrez ID		57554	4835
HPRD ID		09930	01190
Ensembl ID		ENSG00000033122	ENSG00000124588
Uniprot IDs		A0A075B6E9	B3KPX6 P16083 Q5TD07
PDB IDs			1QR2 1SG0 1XI2 1ZX1 2BZS 2QMY 2QMZ 2QR2 2QWX 2QX4 2QX6 2QX8 2QX9 3FW1 3G5M 3GAM 3NFR 3NHF 3NHJ 3NHK 3NHL 3NHP 3NHR 3NHS 3NHU 3NHW 3NHY 3O2N 3O73 3OVM 3OWH 3OWX 3OX1 3OX2 3OX3 3TE7 3TEM 3TZB 3UXE 3UXH 4FGJ 4FGK 4FGL 4GQI 4GR9 4QOD 4QOE 4QOF 4QOG 4QOH 4QOI 4QOJ 4U7F 4U7G 4U7H 4XDG 4XDH 4ZVK 4ZVL 4ZVM 4ZVN 5BUC 5LBT 5LBU 5LBW 5LBY 5LBZ
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?