COG6 and RAB6B

Number of citations of the paper that reports this interaction (PubMedID 27107012)
28

Data Source:
BioGRID (two hybrid)

		COG6	RAB6B
Description		component of oligomeric golgi complex 6	RAB6B, member RAS oncogene family
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Golgi Transport Complex Trans-Golgi Network Membrane	Golgi Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Cytosol Endomembrane System Cytoplasmic Vesicle Presynapse
	Molecular Function	Protein Binding	GTPase Activity Protein Binding GTP Binding Myosin V Binding
	Biological Process	ER To Golgi Vesicle-mediated Transport Intra-Golgi Vesicle-mediated Transport Protein Transport Glycosylation	Intracellular Protein Transport Retrograde Vesicle-mediated Transport, Golgi To ER Intra-Golgi Vesicle-mediated Transport Rab Protein Signal Transduction Retrograde Transport, Endosome To Golgi
Pathways		COPI-mediated anterograde transport Intra-Golgi traffic Retrograde transport at the Trans-Golgi-Network	COPI-independent Golgi-to-ER retrograde traffic Retrograde transport at the Trans-Golgi-Network TBC/RABGAPs RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Asthma ( 30929738) Asthma (adult onset) ( 30929738) Eosinophil counts ( 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 27863252) Height ( 31562340) Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular) ( 23603761) Menarche (age at onset) ( 25231870) Multiple sclerosis ( 31604244 24076602) Neutrophil percentage of granulocytes ( 27863252) Peripheral arterial disease (traffic-related air pollution interaction) ( 27082954) Psoriasis ( 25903422 18369459) Rheumatoid arthritis ( 30423114 24390342) Rheumatoid arthritis (ACPA-positive) ( 23143596 24532676) Sum eosinophil basophil counts ( 27863252) Systemic lupus erythematosus or rheumatoid arthritis ( 27193031)	Blood protein levels ( 30072576) Immune reponse to smallpox (secreted IL-1beta) ( 22610502) Iron status biomarkers (total iron binding capacity) ( 28334935) Post bronchodilator FEV1/FVC ratio ( 26634245)
Interacting Genes		17 interacting genes: ARHGEF5 ATXN7 BCL10 CCDC92 CCHCR1 CNN1 FAM90A1 FANCG GOLGA2 GRAP2 LGALS14 MCM7 NDUFA5 NTAQ1 RAB6B SCNM1 ZBTB16	9 interacting genes: ACVR1 BMPR1B COG6 ERC1 KIF20A LNX2 RABGAP1 SMAD1 TGFBR1
Entrez ID		57511	51560
HPRD ID		08445	11474
Ensembl ID		ENSG00000133103	ENSG00000154917
Uniprot IDs		A0A024RDW5 A0A140VJG7 Q9Y2V7	Q9NRW1
PDB IDs			2E9S 2FE4 2FFQ
Enriched GO Terms of Interacting Partners?
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