MTA3 and FOXK2

Number of citations of the paper that reports this interaction (PubMedID 27773593)
18

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, biochemical, pull down)

		MTA3	FOXK2
Description		metastasis associated 1 family member 3	forkhead box K2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm NuRD Complex Intracellular Membrane-bounded Organelle	Nuclear Chromatin Cell Nucleus Nucleoplasm Mitochondrion Intracellular Membrane-bounded Organelle
	Molecular Function	RNA Polymerase II Repressing Transcription Factor Binding Chromatin Binding Transcription Coactivator Activity Transcription Corepressor Activity Protein Binding Zinc Ion Binding Histone Deacetylase Binding Sequence-specific DNA Binding Protein-containing Complex Binding	Magnesium Ion Binding Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Cell Proliferation Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Histone Deacetylation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Nucleic Acid-templated Transcription	Negative Regulation Of Transcription By RNA Polymerase II Cellular Glucose Homeostasis Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Autophagy Regulation Of Glucose Metabolic Process Protein Deubiquitination Response To Starvation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Canonical Glycolysis
Pathways		HDACs deacetylate histones ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression RNA Polymerase I Transcription Initiation Regulation of PTEN gene transcription Regulation of PTEN gene transcription	UCH proteinases
Drugs
Diseases
GWAS		Breastfeeding duration ( 25475840)	Heel bone mineral density ( 30598549) Lean body mass ( 28552196) Letter-number span reordering ( 31596458) Red cell distribution width ( 27863252 28957414) Reticulocyte count ( 27863252) Reticulocyte fraction of red cells ( 27863252)
Interacting Genes		20 interacting genes: AKT1 ARNT ATM AURKA BAG4 BCAR3 BCL6 CDKN2C FGFR2 FGFR4 FOXK2 FZR1 GRB2 IGF1R KDM1A NACC2 NOTCH2 PARP1 TGFB1 TSG101	10 interacting genes: ESR1 HCFC1 IL2 MTA3 RBBP4 RBBP7 RCOR1 SIN3A TBL1X TBL1XR1
Entrez ID		57504	3607
HPRD ID		12359	00982
Ensembl ID		ENSG00000057935	ENSG00000141568
Uniprot IDs		F6RRE2 Q9BTC8	Q01167
PDB IDs			1JXS 2C6Y
Enriched GO Terms of Interacting Partners?
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