ZNF490 and TBX21

Number of citations of the paper that reports this interaction (PubMedID 20211142)
329

Data Source:
BioGRID (two hybrid)

		ZNF490	TBX21
Description		zinc finger protein 490	T-box transcription factor 21
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleus Neuronal Cell Body
	Molecular Function	DNA Binding Protein Binding Metal Ion Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase II Activating Transcription Factor Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Transcription Regulatory Region DNA Binding
	Biological Process	Regulation Of Transcription, DNA-templated	Negative Regulation Of Transcription By RNA Polymerase II Cell Fate Specification Heart Looping Regulation Of Transcription, DNA-templated Multicellular Organism Development Response To Virus T Cell Differentiation Negative Regulation Of Interleukin-2 Production Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of T Cell Differentiation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Isotype Switching To IgG Isotypes Cellular Response To Organic Substance Lymphocyte Migration Negative Regulation Of T-helper 17 Cell Differentiation Negative Regulation Of T-helper 17 Cell Lineage Commitment Negative Regulation Of T-helper 2 Cell Cytokine Production
Pathways		Generic Transcription Pathway
Drugs
Diseases
GWAS			Ankylosing spondylitis ( 23749187) Asthma ( 30929738 31619474) Asthma (childhood onset) ( 31036433) Body mass index ( 26426971 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index in physically inactive individuals ( 28448500) Diverticular disease ( 30177863) Mean corpuscular hemoglobin ( 27863252) Mean corpuscular volume ( 27863252) Multiple sclerosis ( 22190364) Simvastatin-induced myopathy ( 31220337)
Interacting Genes		21 interacting genes: CCDC136 CCNDBP1 CEP70 DTNBP1 HOXB13 KRT40 KRTAP10-3 KRTAP10-7 LMNA LZTR1 LZTS2 MDFI MTUS2 NDEL1 RBMX RNPS1 TBX21 TRIM41 TSGA10 ZBTB32 ZC4H2	3 interacting genes: EXOC5 HOXC11 ZNF490
Entrez ID		57474	30009
HPRD ID		15802	05355
Ensembl ID		ENSG00000188033	ENSG00000073861
Uniprot IDs		Q9ULM2	Q9UL17
PDB IDs
Enriched GO Terms of Interacting Partners?
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