PTGER2 and PTGDS

Number of citations of the paper that reports this interaction (PubMedID 8163486)
33

Data Source:
HPRD (in vivo)

		PTGER2	PTGDS
Description		prostaglandin E receptor 2	prostaglandin D2 synthase
Image		No pdb structure
GO Annotations	Cellular Component	Cell Plasma Membrane Integral Component Of Plasma Membrane	Extracellular Region Extracellular Space Endoplasmic Reticulum Membrane Rough Endoplasmic Reticulum Golgi Apparatus Nuclear Membrane Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	Prostaglandin E Receptor Activity	Prostaglandin-D Synthase Activity Retinoid Binding Fatty Acid Binding Protein Binding
	Biological Process	Inflammatory Response G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Response To Lipopolysaccharide Response To Progesterone Regulation Of Cell Proliferation Cellular Response To Prostaglandin E Stimulus Positive Regulation Of Gastric Mucosal Blood Circulation	Prostaglandin Biosynthetic Process Cyclooxygenase Pathway Regulation Of Circadian Sleep/wake Cycle, Sleep
Pathways		Prostanoid ligand receptors G alpha (s) signalling events ADORA2B mediated anti-inflammatory cytokines production	Synthesis of Prostaglandins (PG) and Thromboxanes (TX)
Drugs		Alprostadil Dinoprostone Misoprostol Gemeprost Limaprost
Diseases
GWAS			Beta-trace protein levels ( 23328707) Blood protein levels ( 30072576 29875488) Corneal structure ( 23291589)
Interacting Genes		3 interacting genes: PTGDS PTGES PTGFR	17 interacting genes: AKT1 ARRB2 ATXN1 BCAT2 CACNA1A CAPN1 EGFR HK2 HK3 HSP90AA1 KRTAP10-3 KRTAP10-7 MLH1 PTGER1 PTGER2 PTGFR SHBG
Entrez ID		5732	5730
HPRD ID		08905	08904
Ensembl ID		ENSG00000125384	ENSG00000107317
Uniprot IDs		P43116	A0A024R8G3 P41222
PDB IDs			2WWP 3O19 3O22 3O2Y 4IMN 4IMO 4ORR 4ORS 4ORU 4ORW 4ORX 4ORY 4OS0 4OS3 4OS8 5WY9
Enriched GO Terms of Interacting Partners?
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