GOPC and CLCN3

Number of citations of the paper that reports this interaction (PubMedID 9843494)
107

Data Source:
HPRD (in vitro, in vivo)

		GOPC	CLCN3
Description		golgi associated PDZ and coiled-coil motif containing	chloride voltage-gated channel 3
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Lysosomal Membrane Golgi Apparatus Plasma Membrane Postsynaptic Density Membrane Cell Junction Trans-Golgi Network Transport Vesicle Dendrite Golgi-associated Vesicle Membrane Protein-containing Complex	Golgi Membrane Cell Endosome Early Endosome Late Endosome Golgi Apparatus Plasma Membrane Integral Component Of Plasma Membrane Synaptic Vesicle External Side Of Plasma Membrane Cell Surface Vesicle Membrane Membrane Integral Component Of Membrane Secretory Granule Transport Vesicle Membrane Cytoplasmic Vesicle Early Endosome Membrane Late Endosome Membrane Specific Granule Intracellular Membrane-bounded Organelle Phagocytic Vesicle
	Molecular Function	Frizzled Binding Protein Binding Protein C-terminus Binding GTPase Regulator Activity Identical Protein Binding Protein Homodimerization Activity Ion Channel Binding	Voltage-gated Chloride Channel Activity Chloride Channel Activity Protein Binding ATP Binding Solute:proton Antiporter Activity PDZ Domain Binding Chloride Ion Binding Volume-sensitive Chloride Channel Activity
	Biological Process	ER To Golgi Vesicle-mediated Transport Golgi To Plasma Membrane Transport Spermatid Nucleus Differentiation Negative Regulation Of Anion Channel Activity Protein Transport Cytoplasmic Sequestering Of CFTR Protein Apical Protein Localization Regulation Of Catalytic Activity Negative Regulation Of Protein Localization To Cell Surface	Regulation Of PH Negative Regulation Of Cell Volume Endosomal Lumen Acidification Chloride Transmembrane Transport Proton Transmembrane Transport
Pathways		RHO GTPases regulate CFTR trafficking	Stimuli-sensing channels
Drugs
Diseases
GWAS		Atrial fibrillation ( 29892015) Colorectal cancer ( 23266556) Facial emotion recognition (fearful faces) ( 28608620) Night sleep phenotypes ( 27126917)	Autism spectrum disorder or schizophrenia ( 28540026) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892) Schizophrenia ( 28991256 25056061 29483656 30285260)
Interacting Genes		60 interacting genes: ABCA1 ADRB1 AKIRIN1 ASIC3 BATF BECN1 C17orf67 CD300C CDKN2C CERCAM CFTR CLCN3 CRHR1 CSPG5 DLEU1 DPYD FAM90A1 FAM9B FOSL2 FZD5 FZD8 GOLGA3 GRID1 GRID2 HCK HNRNPLL IGHG3 JUN KPNA1 LCLAT1 MORN4 MRPL1 MYLK MYOCD NOTCH1 NUP62 PARK7 PID1 PWWP3A RELA RHOQ RNF183 RNF220 RPL13AP17 RPS6KA1 RTKN SEMA4G SLC25A18 SPATA8 SSTR5 STARD3 STX6 TGFBR2 VIM VTN ZBTB49 ZNF564 ZNF581 ZNF587 ZSCAN1	6 interacting genes: CFTR DNAJC5 GOPC HSPB1 PDZK1 SLC9A3R1
Entrez ID		57120	1182
HPRD ID		06024	02785
Ensembl ID		ENSG00000047932	ENSG00000109572
Uniprot IDs		Q9HD26	B3KXK0 P51790
PDB IDs		2DC2 2LOB 4E34 4E35 4JOE 4JOF 4JOG 4JOH 4JOJ 4JOK 4JOP 4JOR 4K6Y 4K72 4K75 4K76 4K78 4NMO 4NMP 4NMQ 4NMR 4NMS 4NMT 4NMV 4Q6H 4Q6S 5IC3 5K4F 6OV7
Enriched GO Terms of Interacting Partners?
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