CAMK1D and ASAH1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		CAMK1D	ASAH1
Description		calcium/calmodulin dependent protein kinase ID	N-acylsphingosine amidohydrolase 1
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GO Annotations	Cellular Component	Intracellular Nucleus Cytoplasm	Extracellular Region Extracellular Space Nucleus Lysosome Early Endosome Endoplasmic Reticulum Lysosomal Lumen Extracellular Exosome Tertiary Granule Lumen Ficolin-1-rich Granule Lumen
	Molecular Function	Protein Serine/threonine Kinase Activity Calmodulin-dependent Protein Kinase Activity Calmodulin Binding ATP Binding	Hydrolase Activity, Acting On Carbon-nitrogen (but Not Peptide) Bonds Hydrolase Activity, Acting On Carbon-nitrogen (but Not Peptide) Bonds, In Linear Amides N-acylsphingosine Amidohydrolase Activity Ceramidase Activity
	Biological Process	Protein Phosphorylation Inflammatory Response Positive Regulation Of Neuron Projection Development Positive Regulation Of CREB Transcription Factor Activity Positive Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Positive Regulation Of Phagocytosis Regulation Of Dendrite Development Positive Regulation Of Respiratory Burst Regulation Of Granulocyte Chemotaxis Positive Regulation Of Neutrophil Chemotaxis	Glycosphingolipid Metabolic Process Keratinocyte Differentiation Neutrophil Degranulation Sphingosine Biosynthetic Process Ceramide Biosynthetic Process Ceramide Catabolic Process Regulation Of Steroid Biosynthetic Process Cellular Response To Tumor Necrosis Factor
Pathways			Glycosphingolipid metabolism Neutrophil degranulation
Drugs		N-(5-METHYL-1H-PYRAZOL-3-YL)-2-PHENYLQUINAZOLIN-4-AMINE
Diseases			Farber lipogranulomatosis; Farber disease
GWAS		Anorexia nervosa ( 23568457) Bipolar disorder ( 31043756) Body mass index ( 28892062) Borderline personality disorder ( 28632202) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Coronary artery aneurysm in Kawasaki disease ( 27171184) Eating disorders ( 23568457) Headache ( 29397368) Height ( 31562340) Household income (MTAG) ( 31844048) Obesity-related traits ( 23251661) QT interval (drug interaction) ( 23459443) Response to cyclophosphamide in systemic lupus erythematosus with lupus nephritis ( 26980576) Tea consumption ( 31046077) Type 2 diabetes ( 22885922 18372903 26961502 20862305 29358691 30297969 26818947 30718926)	Atrial fibrillation ( 28416818 30061737 29892015) Night sleep phenotypes ( 27126917) Obesity ( 21552555)
Interacting Genes		12 interacting genes: APP ASAH1 BNIP3L CAMKK1 CDC25A CUL3 GMFG LRRK2 NEDD4 NEDD4L POT1 TNFSF13	6 interacting genes: CAMK1D HSPB2 SETDB1 SMPD1 SRPK1 TSC22D1
Entrez ID		57118	427
HPRD ID		06409	01969
Ensembl ID		ENSG00000183049	ENSG00000104763
Uniprot IDs		Q5SQQ7 Q8IU85	A8K0B6 Q13510 Q53H01
PDB IDs		2JC6 6T28 6T29	5U7Z 6MHM
Enriched GO Terms of Interacting Partners?
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