TRPC7 and TRPC3

Number of citations of the paper that reports this interaction (PubMedID 12032305)
213

Data Source:
BioGRID (fluorescent resonance energy transfer)

		TRPC7	TRPC3
Description		transient receptor potential cation channel subfamily C member 7	transient receptor potential cation channel subfamily C member 3
Image		No pdb structure
GO Annotations	Cellular Component	Cell Nuclear Envelope Cis-Golgi Network Plasma Membrane Integral Component Of Plasma Membrane Cation Channel Complex Perinuclear Region Of Cytoplasm	Cell Plasma Membrane Integral Component Of Plasma Membrane Cation Channel Complex
	Molecular Function	Protein Binding Store-operated Calcium Channel Activity Inositol 1,4,5 Trisphosphate Binding	Calcium Channel Activity Protein Binding Store-operated Calcium Channel Activity Inositol 1,4,5 Trisphosphate Binding
	Biological Process	Manganese Ion Transport Single Fertilization Platelet Activation Regulation Of Cytosolic Calcium Ion Concentration Calcium Ion Transmembrane Transport	Calcium Ion Transport Manganese Ion Transport Single Fertilization Phototransduction Positive Regulation Of Calcium Ion Transport Into Cytosol Platelet Activation Response To ATP Regulation Of Cytosolic Calcium Ion Concentration Response To Calcium Ion Calcium Ion Transmembrane Transport Positive Regulation Of Cardiac Muscle Hypertrophy In Response To Stress
Pathways		Effects of PIP2 hydrolysis Elevation of cytosolic Ca2+ levels TRP channels Role of second messengers in netrin-1 signaling	Effects of PIP2 hydrolysis Elevation of cytosolic Ca2+ levels TRP channels Role of second messengers in netrin-1 signaling MECP2 regulates neuronal receptors and channels
Drugs
Diseases
GWAS		Body fat percentage ( 31752434) Docetaxel-induced peripheral neuropathy in metastatic castrate-resistant prostate cancer ( 27143689) Sleep duration (short sleep) ( 30846698)	Celiac disease and Rheumatoid arthritis ( 26546613) Emphysema imaging phenotypes ( 26030696) Rosacea symptom severity ( 29771307)
Interacting Genes		4 interacting genes: ITPR3 MX1 TRPC3 TRPC6	20 interacting genes: CALM1 FKBP1A GNA11 ITPR1 ITPR3 MX1 NAPA ORAI1 PLCB1 PLCB2 PLCB3 PLCG1 PRKCA PRKG1 SLC8A1 STX3 TRPC1 TRPC6 TRPC7 VAMP2
Entrez ID		57113	7222
HPRD ID		18228	15999
Ensembl ID		ENSG00000069018	ENSG00000138741
Uniprot IDs		Q9HCX4	Q13507
PDB IDs			5ZBG 6CUD 6D7L 6DJS
Enriched GO Terms of Interacting Partners?
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