PLSCR4 and APLN

Number of citations of the paper that reports this interaction (PubMedID 21516116)
94

Data Source:
BioGRID (two hybrid)

		PLSCR4	APLN
Description		phospholipid scramblase 4	apelin
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Integral Component Of Membrane	Extracellular Region Extracellular Space Perinuclear Region Of Cytoplasm
	Molecular Function	Calcium Ion Binding Protein Binding SH3 Domain Binding Phospholipid Scramblase Activity Enzyme Binding CD4 Receptor Binding	Signaling Receptor Binding Hormone Activity Apelin Receptor Binding Identical Protein Binding
	Biological Process	Phospholipid Scrambling Cellular Response To Lipopolysaccharide	Angiogenesis Regulation Of The Force Of Heart Contraction Immune Response Signal Transduction G Protein-coupled Receptor Signaling Pathway Gastrulation Lactation Negative Regulation Of Gene Expression Viral Process Positive Regulation Of Heat Generation Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Positive Regulation Of Phosphorylation Drinking Behavior Regulation Of Respiratory Gaseous Exchange Negative Regulation Of Blood Pressure Positive Regulation Of Heart Contraction Negative Regulation Of Vasoconstriction Positive Regulation Of Corticotropin Secretion Positive Regulation Of Corticotropin-releasing Hormone Secretion Apelin Receptor Signaling Pathway Coronary Vasculature Development Positive Regulation Of Pri-miRNA Transcription By RNA Polymerase II Positive Regulation Of G Protein-coupled Receptor Internalization Negative Regulation Of Vascular Smooth Muscle Cell Proliferation Positive Regulation Of Vascular Endothelial Cell Proliferation
Pathways			Peptide ligand-binding receptors G alpha (i) signalling events
Drugs
Diseases
GWAS
Interacting Genes		9 interacting genes: ABHD17A APLN EFEMP2 KRTAP4-12 LPXN MTUS2 NOTCH2NLA PLSCR1 TRIP13	6 interacting genes: APLNR GET3 MDFI PLSCR4 PSMA3 RBPMS
Entrez ID		57088	8862
HPRD ID		07401	02246
Ensembl ID		ENSG00000114698	ENSG00000171388
Uniprot IDs		E9PHR9 Q9NRQ2	Q9ULZ1
PDB IDs		3Q5U
Enriched GO Terms of Interacting Partners?
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