CCDC47 and SARM1

Number of citations of the paper that reports this interaction (PubMedID 21903422)
114

Data Source:
BioGRID (affinity chromatography technology, pull down)

		CCDC47	SARM1
Description		coiled-coil domain containing 47	sterile alpha and TIR motif containing 1
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Integral Component Of Membrane Rough Endoplasmic Reticulum Membrane	Cytoplasm Mitochondrion Cytosol Microtubule Cell Junction Axon Dendrite Extrinsic Component Of Mitochondrial Outer Membrane Synapse
	Molecular Function	RNA Binding Calcium Ion Binding Protein Binding	NAD+ Nucleosidase Activity Protein Binding Signaling Adaptor Activity NAD(P)+ Nucleosidase Activity NAD+ Nucleotidase, Cyclic ADP-ribose Generating
	Biological Process	Osteoblast Differentiation ER Overload Response Endoplasmic Reticulum Organization Post-embryonic Development Ubiquitin-dependent ERAD Pathway Endoplasmic Reticulum Calcium Ion Homeostasis ERAD Pathway	Signal Transduction Response To Glucose Positive Regulation Of Signal Transduction NAD Catabolic Process Negative Regulation Of MyD88-independent Toll-like Receptor Signaling Pathway Regulation Of Apoptotic Process Innate Immune Response Response To Axon Injury Regulation Of Dendrite Morphogenesis Regulation Of Neuron Death Positive Regulation Of Neuron Death
Pathways
Drugs
Diseases
GWAS			Amyotrophic lateral sclerosis ( 27455348) Amyotrophic lateral sclerosis (sporadic) ( 28931804) Blood protein levels ( 29875488 28240269) Osteoprotegerin levels ( 25080503)
Interacting Genes		7 interacting genes: IRAK1 IRF7 RPL7A SARM1 STING1 TIRAP TOM1L1	6 interacting genes: CCDC47 IRAK2 MYD88 NLRX1 STT3A TICAM2
Entrez ID		57003	23098
HPRD ID		17041	09664
Ensembl ID		ENSG00000108588	ENSG00000004139
Uniprot IDs		Q96A33	Q05B42 Q0D2N8 Q6SZW1
PDB IDs			6O0Q 6O0R 6O0S 6O0T 6O0U 6O0V 6O1B 6QWV
Enriched GO Terms of Interacting Partners?
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