LHX9 and KHK

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid, two hybrid)

		LHX9	KHK
Description		LIM homeobox 9	ketohexokinase
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GO Annotations	Cellular Component	Nuclear Chromatin Nucleus	Cytoplasm Cytosol Extracellular Exosome
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Transcription Corepressor Activity Protein Binding Metal Ion Binding	Ketohexokinase Activity Protein Binding ATP Binding Carbohydrate Kinase Activity
	Biological Process	Cell Proliferation Male Gonad Development Female Gonad Development Neuron Differentiation Gonad Morphogenesis Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Dorsal Spinal Cord Interneuron Anterior Axon Guidance	Fructose Metabolic Process Response To Sucrose Response To Glucose Response To Fructose Response To Zinc Ion Response To Insulin Carbohydrate Phosphorylation Fructose Catabolic Process To Hydroxyacetone Phosphate And Glyceraldehyde-3-phosphate Regulation Of Glycogen Metabolic Process
Pathways		Regulation of expression of SLITs and ROBOs	Essential fructosuria Fructose catabolism
Drugs
Diseases
GWAS		General risk tolerance (MTAG) ( 30643258) Heel bone mineral density ( 30598549)	Self-reported risk-taking behaviour ( 30181555)
Interacting Genes		5 interacting genes: CWF19L2 KHK LDB2 SMAD2 SMURF1	2 interacting genes: GLP1R LHX9
Entrez ID		56956	3795
HPRD ID		07299	11774
Ensembl ID		ENSG00000143355	ENSG00000138030
Uniprot IDs		H0YL54 Q9NQ69	A0A140VJM6 P50053
PDB IDs		2DMQ	2HLZ 2HQQ 2HW1 3B3L 3NBV 3NBW 3NC2 3NC9 3NCA 3Q92 3QA2 3QAI 3RO4 5WBM 5WBO 5WBP 5WBQ 5WBR 5WBZ
Enriched GO Terms of Interacting Partners?
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