PRTFDC1 and DTNB

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PRTFDC1	DTNB
Description		phosphoribosyl transferase domain containing 1	dystrobrevin beta
Image			No pdb structure
GO Annotations	Cellular Component		Cytoplasm
	Molecular Function	Nucleotide Binding Magnesium Ion Binding Hypoxanthine Phosphoribosyltransferase Activity Protein Binding Protein Homodimerization Activity	Protein Binding Zinc Ion Binding
	Biological Process	Purine Ribonucleoside Salvage Guanine Salvage GMP Catabolic Process
Pathways
Drugs
Diseases
GWAS		Diisocyanate-induced asthma ( 25918132) Granulocyte count ( 27863252) High light scatter reticulocyte count ( 27863252) High light scatter reticulocyte percentage of red cells ( 27863252) Immature fraction of reticulocytes ( 27863252) Intraocular pressure ( 29617998) Lymphocyte counts ( 27863252) Metabolite levels (Pyroglutamine) ( 23934736) Monocyte count ( 27863252) Myeloid white cell count ( 27863252) Neutrophil count ( 27863252) Obesity-related traits ( 23251661) Perceived intensity of neohesperidin dihydrochalcone ( 31005972) Platelet count ( 27863252) Plateletcrit ( 27863252) Post-traumatic stress disorder ( 25456346) Red cell distribution width ( 27863252) Reticulocyte count ( 27863252) Reticulocyte fraction of red cells ( 27863252) Sum basophil neutrophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) White blood cell count ( 27863252)	B-cell malignancies (chronic lymphocytic leukemia, Hodgkin lymphoma or multiple myeloma) (pleiotropy) ( 28112199) Body mass index ( 26426971) Body mass index (age <50) ( 26426971) Body mass index (age>50) ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Decreased low contrast letter acuity in multiple sclerosis ( 31289819) Height ( 18391951) Heschl's gyrus morphology ( 25130324) Intracranial aneurysm ( 29531279) LDL cholesterol ( 21347282) Macular thickness ( 30535121) Multiple myeloma ( 22120009 26007630) Multiple myeloma and monoclonal gammopathy ( 26007630) Resistant hypertension ( 31545351) Response to platinum-based chemotherapy (cisplatin) ( 21844884) Type 2 diabetes ( 30297969) Waist circumference adjusted for body mass index ( 28552196) Working memory ( 31598132)
Interacting Genes		14 interacting genes: DTNB EEF2KMT EPM2AIP1 EWSR1 FLAD1 GNPDA1 HPRT1 LGALS9B MCMBP NIF3L1 RAB18 STAT5A TCL1A TMEM14B	30 interacting genes: ABI2 ABI3 BEGAIN CCDC85B CEP55 CEP63 DMD DTNBP1 GGA1 HMG20A KIF5A KIF5B KRT31 KRT40 MTUS2 NDEL1 NUP62 PPFIA1 PPFIBP2 PRTFDC1 SNTG1 SNTG2 SPZ1 TRAF2 TSACC TXLNA USHBP1 UTRN VCP ZBTB9
Entrez ID		56952	1838
HPRD ID		17917	09091
Ensembl ID		ENSG00000099256	ENSG00000138101
Uniprot IDs		Q9NRG1	B7Z202 B7Z6A9 E7EVB6 E9PEY4 O60941 Q1I0L3
PDB IDs		2JBH
Enriched GO Terms of Interacting Partners?
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