TRIM39 and UBXN1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		TRIM39	UBXN1
Description		tripartite motif containing 39	UBX domain protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Mitochondrion Cytosol	Nucleus Cytoplasm Endoplasmic Reticulum Cytosol Dendrite VCP-NPL4-UFD1 AAA ATPase Complex Neuronal Cell Body
	Molecular Function	Protein Binding Zinc Ion Binding Transferase Activity Identical Protein Binding	Protein Binding Polyubiquitin Modification-dependent Protein Binding Ubiquitin Protein Ligase Binding K48-linked Polyubiquitin Modification-dependent Protein Binding Ubiquitin Binding ATPase Binding K6-linked Polyubiquitin Modification-dependent Protein Binding Proteasome Regulatory Particle Binding
	Biological Process	Apoptotic Process Mitotic G2 DNA Damage Checkpoint Protein Ubiquitination Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Protein Stabilization Regulation Of Cell Cycle G1/S Phase Transition Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Apoptotic Signaling Pathway	Protein Folding Viral Process Negative Regulation Of Protein Ubiquitination Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Protein K48-linked Deubiquitination Negative Regulation Of ERAD Pathway Negative Regulation Of Ubiquitin-specific Protease Activity
Pathways		Antigen processing: Ubiquitination & Proteasome degradation	N-glycan trimming in the ER and Calnexin/Calreticulin cycle
Drugs
Diseases
GWAS		Asthma (adult onset) ( 31036433) Asthma (childhood onset) ( 31036433) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Cutaneous lupus erythematosus ( 25827949) Neuroticism ( 29255261)	Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		55 interacting genes: APP CACTIN CCNC DCUN1D1 DCX DIP2A EIF4A2 EPHB6 HINFP KDM1A LMNA LNX1 LXN MED18 MNAT1 OTUB2 OTUD6A PDLIM5 PLCD4 POLI PRPF3 PSMA6 PSMD9 RECK RNF166 SMCO3 TP53 TRIM17 TRIM21 TRIM8 TTC32 UBAC1 UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2K UBE2L3 UBE2N UBE2V1 UBE2W UBTD1 UBTD2 UBXN1 UBXN6 USP2 USP39 USP5 WDFY3 ZKSCAN4 ZNF26	15 interacting genes: ACVR1 BARD1 BMPR1B BRCA1 FAM189A2 HOMER2 PLA2G4A PLAA SMAD1 SMURF1 TGFBR1 TRIM39 UBC UBE2I UBQLN1
Entrez ID		56658	51035
HPRD ID		09298	11266
Ensembl ID		ENSG00000204599	ENSG00000162191
Uniprot IDs		A0A024RCP5 A0A024RCR1 Q9HCM9	A0A024R539 A0A024R598 A0A087WTZ5 Q04323
PDB IDs		2DID 2DIF 2ECJ
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?