DIABLO and BIRC7

Number of citations of the paper that reports this interaction (PubMedID 11801603)
26

Data Source:
HPRD (in vivo, in vitro)

		DIABLO	BIRC7
Description		diablo IAP-binding mitochondrial protein	baculoviral IAP repeat containing 7
Image
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Intermembrane Space Cytosol Cytoplasmic Side Of Plasma Membrane CD40 Receptor Complex	Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Centrosome Cytosol
	Molecular Function	Protein Binding	Ubiquitin-protein Transferase Activity Cysteine-type Endopeptidase Inhibitor Activity Protein Binding Enzyme Binding Cysteine-type Endopeptidase Inhibitor Activity Involved In Apoptotic Process Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Apoptotic Process Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Intrinsic Apoptotic Signaling Pathway In Response To Oxidative Stress Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process By Cytochrome C Positive Regulation Of Apoptotic Process Neuron Apoptotic Process Intrinsic Apoptotic Signaling Pathway	Apoptotic Process Activation Of JUN Kinase Activity Protein Ubiquitination Positive Regulation Of Protein Ubiquitination Regulation Of Cell Proliferation Negative Regulation Of Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Natural Killer Cell Apoptotic Process Inhibition Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Pathways		Release of apoptotic factors from the mitochondria SMAC (DIABLO) binds to IAPs SMAC (DIABLO) binds to IAPs SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes SMAC, XIAP-regulated apoptotic response Regulation of the apoptosome activity
Drugs		Phenethyl Isothiocyanate
Diseases
GWAS
Interacting Genes		23 interacting genes: AGTRAP AREL1 ARL6IP1 ARNT BEX3 BIRC2 BIRC3 BIRC5 BIRC6 BIRC7 CASP9 E2F1 EEF1A1 HTRA2 LTBR MAML2 NR4A1 SBNO1 SLC25A47 UBE2K UFM1 XIAP ZNF746	17 interacting genes: CASP3 CASP7 CASP9 DDX6 DIABLO FAM124B HTRA2 PHF1 POLR1C PTCD3 TLE5 UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2I UBE2K
Entrez ID		56616	79444
HPRD ID		05560	05761
Ensembl ID		ENSG00000184047	ENSG00000101197
Uniprot IDs		A0A024RBT2 A0A0S2Z5P6 A0A0S2Z5U7 K7X1S0 Q502X2 Q9NR28	Q96CA5
PDB IDs		1FEW 1G3F 1G73 1OXQ 1TW6 1XB0 1XB1 3D9U 3UIH 3UIJ 4TX5	1OXN 1OXQ 1OY7 1TW6 2I3H 2I3I 3F7G 3F7H 3F7I 3GT9 3GTA 3UW5 4AUQ
Enriched GO Terms of Interacting Partners?
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