PRMT8 and ZNF451

Number of citations of the paper that reports this interaction (PubMedID 23455924)
38

Data Source:
BioGRID (two hybrid)

		PRMT8	ZNF451
Description		protein arginine methyltransferase 8	zinc finger protein 451
Image
GO Annotations	Cellular Component	Nucleus Plasma Membrane Anchored Component Of The Cytoplasmic Side Of The Plasma Membrane	Nucleus PML Body
	Molecular Function	Protein Binding Histone-arginine N-methyltransferase Activity S-adenosylmethionine-dependent Methyltransferase Activity Enzyme Binding Protein-arginine Omega-N Monomethyltransferase Activity Protein-arginine Omega-N Asymmetric Methyltransferase Activity Identical Protein Binding Protein Homodimerization Activity S-adenosyl-L-methionine Binding	Transcription Corepressor Activity Protein Binding Metal Ion Binding SUMO Ligase Activity
	Biological Process	Protein Methylation Histone Methylation Peptidyl-arginine Methylation Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Histone Arginine Methylation Regulation Of Protein Binding Protein Homooligomerization	Regulation Of Gene Expression Protein Sumoylation Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Transcription Initiation From RNA Polymerase II Promoter Negative Regulation Of Histone H3-K9 Acetylation
Pathways
Drugs
Diseases
GWAS		Cardiac Troponin-T levels ( 31014085) Erosive tooth wear (severe vs non-severe) ( 29898447) Erosive tooth wear (severe vs none or mild) ( 29898447) Gut microbiota (bacterial taxa) ( 27723756) HDL cholesterol ( 19060911)
Interacting Genes		13 interacting genes: CEP162 COIL DCAF8 ERC1 GPATCH2L H4C1 OFCC1 PPARA PRMT1 SERBP1 TAF15 VHL ZNF451	29 interacting genes: AR CALCOCO2 CDC5L CDCA4 CPTP CREB1 CREBBP FAM118A FXR2 HTT JMJD6 KDM1A LZTR1 PCBD1 PIAS1 PIAS2 PIK3R3 PML PRMT1 PRMT8 PRPF40A RAP1GDS1 RNF40 SNIP1 SUMO1 SUMO2 SUV39H1 UBC UBE2I
Entrez ID		56341	26036
HPRD ID		11029	10332
Ensembl ID		ENSG00000111218	ENSG00000112200
Uniprot IDs		Q59GT2 Q9NR22	B4DYS2 Q96JY2 Q9Y4E5
PDB IDs		4X41 5DST	5D2M
Enriched GO Terms of Interacting Partners?
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