PRKCI and RBM14

Number of citations of the paper that reports this interaction (PubMedID 30217970)
1

Data Source:
BioGRID (two hybrid)

		PRKCI	RBM14
Description		protein kinase C iota	RNA binding motif protein 14
Image
GO Annotations	Cellular Component	Golgi Membrane Nucleus Nucleoplasm Endosome Cytosol Plasma Membrane Bicellular Tight Junction Microtubule Cytoskeleton Apical Plasma Membrane Cell Leading Edge Schmidt-Lanterman Incisure Intercellular Bridge Extracellular Exosome Schaffer Collateral - CA1 Synapse Glutamatergic Synapse	Nucleus Nucleoplasm Transcription Factor Complex Nucleolus Cytoplasm Nuclear Speck Ribonucleoprotein Complex
	Molecular Function	Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Kinase C Activity Calcium-dependent Protein Kinase C Activity Protein Binding ATP Binding Phospholipid Binding Metal Ion Binding	RNA Binding MRNA Binding Protein Binding Nuclear Receptor Transcription Coactivator Activity
	Biological Process	Protein Phosphorylation Protein Targeting To Membrane Cytoskeleton Organization Actin Filament Organization Positive Regulation Of Neuron Projection Development Vesicle-mediated Transport Cell Migration Peptidyl-serine Phosphorylation Cellular Response To Insulin Stimulus Negative Regulation Of Glial Cell Apoptotic Process Establishment Of Apical/basal Cell Polarity Intracellular Signal Transduction Eye Photoreceptor Cell Development Negative Regulation Of Apoptotic Process Negative Regulation Of Neuron Apoptotic Process Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Cell-cell Junction Organization Positive Regulation Of Notch Signaling Pathway Positive Regulation Of Glucose Import Secretion Golgi Vesicle Budding Positive Regulation Of NF-kappaB Transcription Factor Activity Positive Regulation Of Glial Cell Proliferation Membrane Organization Response To Interleukin-1 Bicellular Tight Junction Assembly Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels Positive Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of Endothelial Cell Apoptotic Process	Activation Of Innate Immune Response Response To Hormone Histone Deacetylation Innate Immune Response Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Centriole Replication SMAD Protein Signal Transduction Centriole Assembly
Pathways		Pre-NOTCH Transcription and Translation p75NTR recruits signalling complexes Tight junction interactions	RUNX2 regulates bone development
Drugs		Tamoxifen Rbt205 Inhibitor
Diseases
GWAS		Microalbuminuria ( 31511532) Prostate cancer ( 25939597) Urinary albumin excretion ( 30220432) Urinary albumin-to-creatinine ratio ( 31630189 31511532)	Bipolar disorder ( 21926972)
Interacting Genes		50 interacting genes: ADAP1 ANXA1 APP BAD CASK CASP8 CCNT1 CDC42 CDK7 CHUK CTBP1 FABP4 FCGR3A FRS2 FRS3 GAPDH HRAS IKBKG IL1RAP IRAK1 MAP2K1 MAP2K5 MAPT MARK4 MBP NFKBIA PARD3 PARD6A PARD6B PARD6G PCM1 PDPK1 PNMA1 RAB2A RAB4A RAC1 RBM14 RHOQ RPA2 SMG1 SMURF1 SQSTM1 SRC TSC22D1 TTR UBC USP20 VHL YWHAH YWHAZ	35 interacting genes: AKAP9 CASK CEP55 CRLF3 CTBP1 DDX17 DDX6 DMRTB1 DYNLT1 EP300 FMR1 FXR2 HNRNPK KIFAP3 KLC4 NCOA6 NDEL1 NR3C1 PARD6G PARP1 PCBP1 PRKCI QKI RBM10 RBM5 RPA2 RUNX1 RUNX2 SLAIN1 SS18 SYT1 TARBP2 UBE2I XRCC5 YWHAE
Entrez ID		5584	10432
HPRD ID		02105	11485
Ensembl ID		ENSG00000163558	ENSG00000239306
Uniprot IDs		P41743	A0A0S2Z4Z0 A0A0S2Z567 A0A0S2Z5V2 Q96PK6
PDB IDs		1VD2 1WMH 1ZRZ 3A8W 3A8X 3ZH8 5LI1 5LI9 5LIH 6ILZ	2DNP
Enriched GO Terms of Interacting Partners?
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