KDM3A and MRTFB

Number of citations of the paper that reports this interaction (PubMedID 17991879)
42

Data Source:
BioGRID (pull down)

		KDM3A	MRTFB
Description		lysine demethylase 3A	myocardin related transcription factor B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytoplasm Membrane	Nucleus
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity Iron Ion Binding Protein Binding Chromatin DNA Binding Histone Demethylase Activity (H3-K9 Specific) Androgen Receptor Binding Dioxygenase Activity	Transcription Coactivator Activity Protein Binding Cadherin Binding
	Biological Process	Regulation Of Transcription, DNA-templated Spermatid Nucleus Elongation Hormone-mediated Signaling Pathway Androgen Receptor Signaling Pathway Histone H3-K9 Demethylation Histone H3-K9 Dimethylation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Formaldehyde Biosynthetic Process Negative Regulation Of Histone H3-K9 Methylation Oxidation-reduction Process Positive Regulation Of Cold-induced Thermogenesis Cellular Response To Leukemia Inhibitory Factor Regulation Of Stem Cell Population Maintenance Regulation Of Stem Cell Differentiation	Muscle Organ Development Positive Regulation Of Striated Muscle Tissue Development Positive Regulation Of Transcription By RNA Polymerase II Smooth Muscle Cell Differentiation
Pathways		HDMs demethylate histones NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux
Drugs
Diseases
GWAS		Atrial fibrillation ( 29892015) Glomerular filtration rate in chronic kidney disease ( 26420894) Ovarian cancer ( 30557369)
Interacting Genes		6 interacting genes: ETV2 H3C14 MRTFA MRTFB MYOCD RIPK2	8 interacting genes: ERC1 KDM3A MRTFA NCOA3 SMAD1 SMAD7 SRF SVIL
Entrez ID		55818	57496
HPRD ID		11054	17577
Ensembl ID		ENSG00000115548	ENSG00000186260
Uniprot IDs		Q9Y4C1	Q9ULH7
PDB IDs
Enriched GO Terms of Interacting Partners?
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