PRKCE and GRM5

  • Number of citations of the paper that reports this interaction (PubMedID 15894802)
  • 29
  • Data Source:
  • HPRD (in vitro)

PRKCE

GRM5

Description protein kinase C epsilon glutamate metabotropic receptor 5
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Attention deficit hyperactivity disorder ( 22012869)
  • Blond vs. brown/black hair color ( 30531825)
  • Coronary artery calcified atherosclerotic plaque score in type 2 diabetes ( 29221444)
  • General factor of neuroticism ( 30867560)
  • Hair color ( 30664655)
  • Hypertension ( 31879980)
  • Neurociticism ( 29500382)
  • Nonsyndromic cleft lip ( 31609978)
  • Rheumatoid arthritis (ACPA-negative) ( 24532677)
  • Skin pigmentation ( 31315583 30664655)
  • Skin pigmentation (conditioned on rs1426654 and rs35397) ( 31315583)
  • Skin, hair and eye pigmentation (multivariate analysis) ( 30664655)
  • Tanning ( 19340012)
Interacting Genes 59 interacting genes: ACTA1 ACTC1 ADAP1 AFAP1 AKAP9 ATF2 BRAF BTK CFTR CHAT CNN1 COPB1 COPB2 DSP EGFR ELAVL1 FYN GAD1 GAD2 GJA1 GNA12 GNA13 GRIN1 GRIN2D GRM5 H1-1 HK2 IKBKB ITGB1 ITGB2 KRT1 KRT18 MAP4K4 MAPK1 MAPK3 MAPT MARK2 MYH2 NANOG NUMB OPRD1 PDLIM5 PDPK1 PECAM1 PIK3CB PPP1R14A PRKD1 RACK1 RAD9A RAF1 RASGRP3 RPS6KB2 SLC25A4 SLC4A3 SNCA SRC TIAM1 TRPV1 VDAC1 19 interacting genes: ACTN1 CALM1 CALM2 CALM3 EFNB2 FLNA GPRASP1 HOMER1 HOMER3 PRKCA PRKCB PRKCD PRKCE PRKCG PRKCQ PRKCZ RGS12 SIAH1 TAMALIN
Entrez ID 5581 2915
HPRD ID 01500 04980
Ensembl ID ENSG00000171132 ENSG00000168959
Uniprot IDs L7RTI5 Q02156 A8K5P7 P41594
PDB IDs 2WH0 5LIH 3LMK 4OO9 5CGC 5CGD 6N4X 6N4Y 6N50 6N51 6N52
Enriched GO Terms of Interacting Partners?
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