DEPDC1B and UHMK1

Number of citations of the paper that reports this interaction (PubMedID 25458010)
15

Data Source:
BioGRID (two hybrid)

		DEPDC1B	UHMK1
Description		DEP domain containing 1B	U2AF homology motif kinase 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol	Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Axon Midbody Dendrite Cytoplasm Neuronal Ribonucleoprotein Granule
	Molecular Function	GTPase Activator Activity	RNA Binding Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Transferase Activity Ribonucleoprotein Complex Binding
	Biological Process	Cell Migration Positive Regulation Of Wnt Signaling Pathway Intracellular Signal Transduction Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction	Cell Cycle Arrest Peptidyl-serine Phosphorylation Neuron Projection Development Positive Regulation Of Translational Initiation Protein Autophosphorylation Regulation Of Protein Export From Nucleus
Pathways		Rho GTPase cycle	Estrogen-dependent nuclear events downstream of ESR-membrane signaling
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Intelligence (MTAG) ( 29326435) Metabolite levels ( 23823483)	Bone mineral density (femoral neck) ( 27424934) Bone mineral density (total hip) ( 27424934) Discordance in emotional problems in monozygotic twins ( 27043157) Takayasu arteritis ( 25604533)
Interacting Genes		6 interacting genes: CDC23 EBPL GRIP1 PTPRF RGS3 UHMK1	3 interacting genes: DEPDC1B PAM STMN1
Entrez ID		55789	127933
HPRD ID		16794	12318
Ensembl ID		ENSG00000035499	ENSG00000152332
Uniprot IDs		Q8WUY9	Q8TAS1
PDB IDs
Enriched GO Terms of Interacting Partners?
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