WDR12 and PPIL3

		WDR12	PPIL3
Description		WD repeat domain 12	peptidylprolyl isomerase like 3
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GO Annotations	Cellular Component	Nucleoplasm Nucleolus Preribosome, Large Subunit Precursor PeBoW Complex	Catalytic Step 2 Spliceosome
	Molecular Function	Protein Binding Ribonucleoprotein Complex Binding	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding
	Biological Process	Maturation Of 5.8S RRNA Maturation Of LSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Maturation Of 5.8S RRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Maturation Of LSU-rRNA RRNA Processing Notch Signaling Pathway Ribosomal Large Subunit Biogenesis Regulation Of Cell Cycle	MRNA Splicing, Via Spliceosome Protein Peptidyl-prolyl Isomerization Protein Folding
Pathways		Major pathway of rRNA processing in the nucleolus and cytosol	mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Coronary artery disease ( 24262325) Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975) Coronary artery disease or ischemic stroke ( 24262325) Coronary artery disease or large artery stroke ( 24262325) Coronary heart disease ( 21378990) Ischemic stroke (small-vessel) ( 29531354) Myocardial infarction (early onset) ( 19198609)	Breast cancer ( 27117709) Breast cancer (estrogen-receptor negative) ( 27117709) Triptolide cytotoxicity ( 26121980)
Interacting Genes		3 interacting genes: H1-2 NOTCH1 PPIL3	15 interacting genes: ALS2 CDK11B MAIP1 MOB4 NOP58 NUP107 PCBP1 SHARPIN SLU7 SPATS2L SRPK1 STRADB TAB2 TAB3 WDR12
Entrez ID		55759	53938
HPRD ID		18295	15163
Ensembl ID		ENSG00000138442	ENSG00000240344
Uniprot IDs		Q53T99 Q9GZL7	A0A024R3V4 A0A0S2Z5A8 Q9H2H8
PDB IDs		6N31 6P0Q	1XYH 2OJU 2OK3
Enriched GO Terms of Interacting Partners?
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