IWS1 and SUPT6H

Number of citations of the paper that reports this interaction (PubMedID 19141475)
102

Data Source:
BioGRID (affinity chromatography technology, pull down)

		IWS1	SUPT6H
Description		interacts with SUPT6H, CTD assembly factor 1	SPT6 homolog, histone chaperone and transcription elongation factor
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GO Annotations	Cellular Component	Nucleus Nucleoplasm	Nucleus Nucleoplasm Transcription Elongation Factor Complex Transcriptionally Active Chromatin
	Molecular Function	Protein Binding	DNA Binding DNA-binding Transcription Factor Activity RNA Binding Protein Binding Nucleosome Binding Histone Binding
	Biological Process	Transcription By RNA Polymerase II Transcription Elongation From RNA Polymerase II Promoter MRNA Processing RNA Splicing Regulation Of MRNA Export From Nucleus Regulation Of MRNA Processing MRNA Transport Regulation Of Histone H4 Acetylation Regulation Of Histone H3-K36 Trimethylation	Blastocyst Formation Chromatin Remodeling Regulation Of Transcription, DNA-templated Transcription By RNA Polymerase II Transcription Elongation From RNA Polymerase II Promoter MRNA Processing RNA Splicing Regulation Of MRNA Export From Nucleus Viral Process Positive Regulation Of Transcription Elongation From RNA Polymerase II Promoter Nucleosome Organization MRNA Transcription By RNA Polymerase II Regulation Of Isotype Switching Regulation Of MRNA Processing MRNA Transport Regulation Of Muscle Cell Differentiation Negative Regulation Of Histone H3-K27 Methylation Chromatin Maintenance
Pathways		Formation of RNA Pol II elongation complex RNA Polymerase II Pre-transcription Events RNA Polymerase II Transcription Elongation	Formation of RNA Pol II elongation complex RNA Polymerase II Pre-transcription Events RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS		Cardiac troponin-I levels ( 31014085)	Pulse pressure ( 30578418)
Interacting Genes		9 interacting genes: AKT1 AKT3 CSNK2A1 ERICH2 KRTAP10-3 POLR2A STAT2 SUPT6H TCEA1	9 interacting genes: AKT1 CSNK2A1 ERBB2 HSP90B1 HSPA9 HSPD1 IWS1 MCPH1 TSC2
Entrez ID		55677	6830
HPRD ID		07639	03211
Ensembl ID		ENSG00000163166	ENSG00000109111
Uniprot IDs		Q96ST2	Q7KZ85
PDB IDs		6EMR	6GME 6GMH
Enriched GO Terms of Interacting Partners?
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