PRPF40A and SDK1

Number of citations of the paper that reports this interaction (PubMedID 15231748)
85

Data Source:
BioGRID (two hybrid)

		PRPF40A	SDK1
Description		pre-mRNA processing factor 40 homolog A	sidekick cell adhesion molecule 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm U1 SnRNP Cytosol Membrane Nuclear Matrix Nuclear Speck U2-type Prespliceosome	Plasma Membrane Integral Component Of Membrane Cell Junction Synapse
	Molecular Function	RNA Binding Protein Binding	Identical Protein Binding
	Biological Process	MRNA Splicing, Via Spliceosome Cytoskeleton Organization Cell Cycle Regulation Of Cell Shape Cell Migration Regulation Of Cytokinesis MRNA Cis Splicing, Via Spliceosome Cell Division	Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Synapse Assembly Retina Layer Formation Cell-cell Junction Organization Behavioral Response To Cocaine Regulation Of Dendritic Spine Development
Pathways		mRNA Splicing - Major Pathway	SDK interactions
Drugs
Diseases
GWAS		Heel bone mineral density ( 30598549) Memory dysfunction in frontotemporal lobe dementia ( 29724592) Metabolite levels ( 23823483) Pulse pressure ( 30224653)	Acute graft versus host disease in bone marrow transplantation (donor effect) ( 27595289) Adventurousness ( 30643258) Anxiety and stress-related disorders ( 31116379) Cannabis use ( 30150663) Cardiac Troponin-T levels ( 31014085) Cognitive decline rate in late mild cognitive impairment ( 26252872) Dimensional psychopathology (Cognitive) ( 29496196) Disease progression in age-related macular degeneration ( 29346644) Dupuytren's disease ( 28886342) Early childhood aggressive behavior ( 26087016) Gastroesophageal reflux disease ( 31527586) Gestational age at birth (child effect) ( 31194736) Liver fibrosis in pediatric non-alcoholic fatty acid liver disease ( 28918882) Moderate-to-late spontaneous preterm birth ( 31194736) Motion sickness ( 25628336) Multisite chronic pain ( 31194737) Obesity-related traits ( 23251661) Quantitative traits ( 19197348) Risk-taking tendency (4-domain principal component model) ( 30643258) Smoking initiation ( 30617275) Smoking initiation (ever regular vs never regular) ( 30679032) Smoking status (ever vs never smokers) ( 30643258) Social science traits (pleiotropy) (HIPO component 1) ( 30289880) Type 2 diabetes ( 30130595)
Interacting Genes		119 interacting genes: ABI1 AKAP8L APBB1IP ARFGEF2 ASXL2 ATAD3A BAG6 BRD4 CAP2 CCT2 CCT4 CCT7 CDK12 CDK13 CHD3 CHERP CPSF6 CUL1 CYFIP1 CYFIP2 DAAM1 DHX15 DHX8 DHX9 DIAPH1 ENAH ERG EVL FASLG FMN1 FMNL1 FMNL2 FMNL3 FN1 FNBP4 FRA10AC1 GAPDH HIPK1 HNRNPF HNRNPK HNRNPU HNRNPUL1 HSPB1 HSPG2 HTT IL1RAP KMT2B LARP7 LTBP3 MAP1LC3A MECP2 MMP11 NCKAP1L NKAP NONO PCBP2 PDCD7 PECAM1 PFKL PIAS1 PIAS3 PIAS4 PPIG PRKAR1A PSG5 PTPRF RBM39 RBMX2 RCC2 RLF RPL4 RPLP0 SDCBP SDCBP2 SDK1 SERPINB9 SF1 SF3A1 SF3A2 SF3A3 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SMAD4 SNIP1 SNRNP70 SON SRPK2 STIM2 TCEAL9 U2AF1 U2AF2 U2SURP UBE2I UBE2K UBQLN1 UBQLN2 UBQLN4 UBR4 VASP VCL WAS WASF2 WASL WBP11 WBP4 WIPF1 XRCC6 YBX1 YLPM1 YWHAG ZCCHC10 ZCCHC8 ZFHX3 ZHX1 ZNF341 ZNF451	4 interacting genes: LNX1 MTDH PRPF40A UBC
Entrez ID		55660	221935
HPRD ID		10995	07388
Ensembl ID		ENSG00000196504	ENSG00000146555
Uniprot IDs		O75400	Q7Z5N4
PDB IDs		1UZC 1YWI 1YWJ 1ZR7 2CQN 2DYF 2KZG 2L5F 2L9V 2LKS
Enriched GO Terms of Interacting Partners?
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