TRPV6 and PDE9A

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		TRPV6	PDE9A
Description		transient receptor potential cation channel subfamily V member 6	phosphodiesterase 9A
Image
GO Annotations	Cellular Component	Cell Plasma Membrane Integral Component Of Plasma Membrane	Endoplasmic Reticulum Golgi Apparatus Cytosol Ruffle Membrane Sarcolemma Perikaryon Perinuclear Region Of Cytoplasm
	Molecular Function	Ion Channel Activity Calcium Channel Activity Protein Binding Calmodulin Binding Metal Ion Binding	3',5'-cyclic-nucleotide Phosphodiesterase Activity Protein Binding Metal Ion Binding 3',5'-cyclic-GMP Phosphodiesterase Activity
	Biological Process	Calcium Ion Transport Regulation Of Calcium Ion-dependent Exocytosis Response To Calcium Ion Calcium Ion Homeostasis Calcium Ion Transmembrane Transport Calcium Ion Import Across Plasma Membrane	Signal Transduction Positive Regulation Of Cardiac Muscle Hypertrophy CGMP-mediated Signaling CGMP Metabolic Process CGMP Catabolic Process
Pathways		TRP channels	cGMP effects
Drugs			Caffeine Gamma-Glutamyl[S-(2-Iodobenzyl)Cysteinyl]Glycine 3-isobutyl-1-methyl-7H-xanthine Trapidil
Diseases
GWAS		Alcoholic chronic pancreatitis ( 28754779) Cancer ( 29299148)	Perceived unattractiveness to mosquitoes ( 28199695)
Interacting Genes		16 interacting genes: CALB1 CALM1 KRT40 KRTAP10-3 KRTAP10-5 KRTAP10-8 MDFI MID2 NEDD4 NOTCH2NLA PDE9A PNMA1 PRKCA PTPN1 S100A10 TRAF1	20 interacting genes: BAG3 C9orf106 CLK1 CRY2 GORASP2 KRTAP10-3 KRTAP10-8 KRTAP4-2 KRTAP9-2 LAGE3 LMO2 NAA38 NOTCH2NLA PCNT PHYHIPL SULT1E1 TFAP4 TRIM32 TRPV6 UTP23
Entrez ID		55503	5152
HPRD ID		05982	09115
Ensembl ID		ENSG00000165125	ENSG00000160191
Uniprot IDs		Q9H1D0	A0A0S2Z475 A0A0S2Z4A3 A0A0S2Z4T6 O76083
PDB IDs		6BO8 6BO9 6BOA 6D7S 6D7T 6E2F	2HD1 2YY2 3DY8 3DYL 3DYN 3DYQ 3DYS 3JSI 3JSW 3K3E 3K3H 3N3Z 3QI3 3QI4 4E90 4G2J 4G2L 4GH6 4Y86 4Y87 4Y8C 6A3N
Enriched GO Terms of Interacting Partners?
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