PPP4C and PPP4R4

Number of citations of the paper that reports this interaction (PubMedID 28514442)
199

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo)

		PPP4C	PPP4R4
Description		protein phosphatase 4 catalytic subunit	protein phosphatase 4 regulatory subunit 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Microtubule Organizing Center Cytosol Plasma Membrane Protein Phosphatase 4 Complex	Cytoplasm Cytosol Protein Serine/threonine Phosphatase Complex
	Molecular Function	NF-kappaB-inducing Kinase Activity Protein Serine/threonine Phosphatase Activity Protein Binding Metal Ion Binding	Protein Binding Protein Phosphatase Regulator Activity
	Biological Process	Protein Dephosphorylation Regulation Of Double-strand Break Repair Via Homologous Recombination NIK/NF-kappaB Signaling	Blastocyst Hatching Negative Regulation Of Phosphoprotein Phosphatase Activity Regulation Of Protein Serine/threonine Phosphatase Activity
Pathways		Processing of DNA double-strand break ends
Drugs
Diseases
GWAS		Adventurousness ( 30643258) Autism spectrum disorder or schizophrenia ( 28540026) Body fat distribution (arm fat ratio) ( 30664634) Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Mean corpuscular volume ( 29403010) Medication use (diuretics) ( 31015401) Schizophrenia ( 25056061 29483656)	Blood protein levels ( 29875488) Chronic obstructive pulmonary disease ( 28166215) Post bronchodilator FEV1 ( 26634245) Post bronchodilator FEV1/FVC ratio ( 26634245)
Interacting Genes		21 interacting genes: CCDC6 DHX38 HDAC3 IGBP1 JUN NFKB1 PPP2R1A PPP2R5D PPP4R1 PPP4R2 PPP4R3B PPP4R4 REL RELA RPA2 TIPRL TK1 TMSB4X TP53 TRAF6 TRIM28	1 interacting genes: PPP4C
Entrez ID		5531	57718
HPRD ID		03615	13878
Ensembl ID		ENSG00000149923	ENSG00000119698
Uniprot IDs		A0A024R625 P60510	Q6NUP7
PDB IDs
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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