RMDN3 and VAPA

Number of citations of the paper that reports this interaction (PubMedID 26496610)
285

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, two hybrid)

		RMDN3	VAPA
Description		regulator of microtubule dynamics 3	VAMP associated protein A
Image		No pdb structure
GO Annotations	Cellular Component	Spindle Pole Cell Nucleus Mitochondrion Mitochondrial Outer Membrane Microtubule Integral Component Of Membrane Intercellular Bridge	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Bicellular Tight Junction Microtubule Cytoskeleton Integral Component Of Membrane Nuclear Membrane Vesicle Azurophil Granule Membrane Perinuclear Region Of Cytoplasm Endoplasmic Reticulum Exit Site
	Molecular Function	Protein Binding	Protein Binding Microtubule Binding Protein Domain Specific Binding FFAT Motif Binding Cadherin Binding Protein Heterodimerization Activity
	Biological Process	Cellular Calcium Ion Homeostasis Apoptotic Process Cell Differentiation	ER To Golgi Vesicle-mediated Transport Endoplasmic Reticulum Organization Cell Death Viral Process Sphingolipid Biosynthetic Process Neuron Projection Development Protein Folding In Endoplasmic Reticulum Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Neutrophil Degranulation Positive Regulation By Host Of Viral Release From Host Cell Negative Regulation By Host Of Viral Genome Replication Positive Regulation By Host Of Viral Genome Replication Membrane Fusion Protein Localization To Endoplasmic Reticulum COPII-coated Vesicle Budding
Pathways			Sphingolipid de novo biosynthesis Neutrophil degranulation Insertion of tail-anchored proteins into the endoplasmic reticulum membrane Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Drugs
Diseases
GWAS		Anxiety and stress-related disorders ( 31116379)	Diverticular disease ( 30177863) FEV1 ( 30804560) Heel bone mineral density ( 30598549) Lung function (FEV1/FVC) ( 30804560) Metabolite levels ( 23823483) Peak expiratory flow ( 30804560) Pulmonary function (smoking interaction) ( 23284291)
Interacting Genes		6 interacting genes: EGFL8 PSEN1 VAPA YWHAB YWHAG YWHAZ	15 interacting genes: ADGRG7 ADRB2 APOD APP CACNG1 EGFR KCNB1 NSF OPRM1 OSBP RMDN3 SIK1 VAMP1 VAMP2 ZBTB22
Entrez ID		55177	9218
HPRD ID		07687	09299
Ensembl ID		ENSG00000137824	ENSG00000101558
Uniprot IDs		A0A024R9P6 Q96TC7	Q9P0L0
PDB IDs			2RR3
Enriched GO Terms of Interacting Partners?
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