UBR7 and ITGB3BP

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		UBR7	ITGB3BP
Description		ubiquitin protein ligase E3 component n-recognin 7	integrin subunit beta 3 binding protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Condensed Chromosome Kinetochore Nucleus Nucleoplasm Cytoplasm Cytosol Membrane
	Molecular Function	Molecular_function Zinc Ion Binding Ubiquitin Protein Ligase Activity	Protein Binding Protein C-terminus Binding
	Biological Process	Biological_process Protein Ubiquitination	Regulation Of Transcription, DNA-templated Apoptotic Process Cell Cycle Cell Adhesion Signal Transduction CENP-A Containing Nucleosome Assembly Positive Regulation Of Apoptotic Process Cell Division
Pathways			Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal NRIF signals cell death from the nucleus NRIF signals cell death from the nucleus Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Body mass index ( 26426971)
Interacting Genes		5 interacting genes: H2BC3 H3C15 ITGB3BP UBE2E1 UBQLN4	22 interacting genes: ACTN2 APP ARFIP2 CCNA2 CERT1 DDX24 ESR1 ITGB3 ITGB5 KDM1A KIFC3 LRRK2 MAPK6 MTA1 NFKB1 PIH1D2 RECQL5 RXRA RXRG SVIL THRA UBR7
Entrez ID		55148	23421
HPRD ID		16602	09267
Ensembl ID		ENSG00000012963	ENSG00000142856
Uniprot IDs		Q8N806	D3DQ59 Q13352
PDB IDs
Enriched GO Terms of Interacting Partners?
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