DUSP23 and MKRN1

Number of citations of the paper that reports this interaction (PubMedID 21900206)
114

		DUSP23	MKRN1
Description		dual specificity phosphatase 23	makorin ring finger protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol	Cellular_component Cytosol
	Molecular Function	Protein Tyrosine Phosphatase Activity Protein Binding Protein Tyrosine/serine/threonine Phosphatase Activity Phosphatase Activity	RNA Binding Ubiquitin-protein Transferase Activity Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Dephosphorylation Peptidyl-tyrosine Dephosphorylation	Protein Polyubiquitination
Pathways			AKT phosphorylates targets in the cytosol Regulation of PTEN stability and activity Antigen processing: Ubiquitination & Proteasome degradation
Drugs		4-Nitrophenyl Phosphate
Diseases
GWAS		Bone mineral density (Ward's triangle area) ( 27397699) C-reactive protein ( 22939635) Interstitial lung disease ( 21787189)	General risk tolerance (MTAG) ( 30643258) Number of sexual partners ( 30643258)
Interacting Genes		24 interacting genes: ASB13 CCDC186 CEP126 DBI DBN1 DNMT3B EDRF1 EED EXOSC8 GCM1 KAT5 KBTBD7 MKRN1 MRPL20 MTFR1 NIF3L1 PRDX4 RPL8 RUFY2 SHC1 SMPD1 TMOD3 TUBA1A ZNF746	8 interacting genes: APC CSNK1G1 DUSP23 EXOSC8 FADD MAP1LC3B UBE2D3 UBE2W
Entrez ID		54935	23608
HPRD ID		07908	09673
Ensembl ID		ENSG00000158716	ENSG00000133606
Uniprot IDs		A0A140VJI5 Q9BVJ7	Q9UHC7
PDB IDs		2IMG 4ERC
Enriched GO Terms of Interacting Partners?
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