CHCHD3 and SAMM50

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		CHCHD3	SAMM50
Description		coiled-coil-helix-coiled-coil-helix domain containing 3	SAMM50 sorting and assembly machinery component
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion Mitochondrial Inner Membrane MICOS Complex Extracellular Exosome	Mitochondrial Sorting And Assembly Machinery Complex Mitochondrion Mitochondrial Outer Membrane Integral Component Of Membrane Extracellular Exosome
	Molecular Function	DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding Phosphatase Binding Molecular Adaptor Activity	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Inner Mitochondrial Membrane Organization Mitochondrial Fusion Cristae Formation	Mitochondrial Respiratory Chain Complex Assembly Cellular Protein-containing Complex Assembly Cristae Formation Protein Import Into Mitochondrial Outer Membrane Protein-containing Complex Assembly
Pathways		Mitochondrial protein import Cristae formation	Mitochondrial protein import Cristae formation
Drugs
Diseases
GWAS		Chronotype ( 30696823) Food allergy ( 29030101) Intercellular adhesion molecule 1 (red blood cell fatty acid level interaction) ( 28820441) Metabolite levels ( 23823483) Peanut allergy ( 29030101) Smoking status (ever vs never smokers) ( 30643258) Urinary potassium excretion ( 31409800)	Alanine aminotransferase levels ( 30718733) Cholesterol, total ( 26780889) Hematological and biochemical traits ( 20139978) Liver enzyme levels ( 18940312) Liver enzyme levels (alanine transaminase) ( 22001757) Metabolite levels ( 23823483) Nonalcoholic fatty liver disease ( 22719876 29271184 29385134) Nonalcoholic steatohepatitis-derived hepatocellular carcinoma ( 29385134) Pediatric non-alcoholic fatty liver disease activity score ( 23535911) Total cholesterol levels ( 28334899) Type 2 diabetes ( 30054458)
Interacting Genes		24 interacting genes: AASS AMOTL2 BLZF1 CALCOCO2 CBY2 CCDC33 CCDC85B FANCL GMCL2 GOLGA2 KRT40 KRTAP4-12 LZTS2 NOTCH2NLA NUDT3 PDE4DIP RAB3IP RPGRIP1 SAMM50 SPAG5 SSX2IP TRAF1 TRIM27 USHBP1	4 interacting genes: CHCHD3 HMGB2 MEOX2 TOMM40
Entrez ID		54927	25813
HPRD ID		13044	10826
Ensembl ID		ENSG00000106554	ENSG00000100347
Uniprot IDs		A4D1N4 B7Z1X9 C9JRZ6 Q9NX63	Q9Y512
PDB IDs
Enriched GO Terms of Interacting Partners?
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