NDE1 and ZNF398

Number of citations of the paper that reports this interaction (PubMedID 24722188)
51

Data Source:
BioGRID (two hybrid)

		NDE1	ZNF398
Description		nudE neurodevelopment protein 1	zinc finger protein 398
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Kinetochore Condensed Chromosome Kinetochore Cell Centrosome Cytosol Kinesin Complex Microtubule Membrane Spindle Pole Centrosome Cleavage Furrow Synapse	Nucleus
	Molecular Function	Protein Binding Microtubule Binding Protein Domain Specific Binding Identical Protein Binding	DNA Binding Protein Binding Metal Ion Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Establishment Of Mitotic Spindle Orientation Neuron Migration Microtubule Nucleation Chromosome Segregation Mitotic Centrosome Separation Neuroblast Proliferation Regulation Of G2/M Transition Of Mitotic Cell Cycle Cell Migration Cerebral Cortex Development Vesicle Transport Along Microtubule Centrosome Duplication Cell Division Establishment Of Chromosome Localization Centrosome Localization Ciliary Basal Body-plasma Membrane Docking Regulation Of Microtubule Motor Activity	Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane RHO GTPases Activate Formins Mitotic Prometaphase AURKA Activation by TPX2 EML4 and NUDC in mitotic spindle formation	Generic Transcription Pathway
Drugs
Diseases
GWAS		Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Multiple system atrophy (pathologically confirmed) ( 27629089) Serum uric acid levels in response to allopurinol in gout ( 25676789)	Eosinophil counts ( 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 27863252) Neutrophil percentage of granulocytes ( 27863252) Sum eosinophil basophil counts ( 27863252)
Interacting Genes		27 interacting genes: AR ARNT2 CDK1 DISC1 FAM9B FBXO7 GOLGA2 HOXA2 LZTS2 MAPK1 MED4 MKRN3 NDC80 PAFAH1B1 REL TFIP11 TRIM27 TSPOAP1 TTC1 TUBG1 UBQLN1 USHBP1 WAC YWHAG YWHAQ ZNF365 ZNF398	15 interacting genes: - C1orf109 CHPF2 CIB3 CLK2 DGCR6 ELMO1 ESR1 GPATCH2L MAGOHB MFAP1 NDE1 OPTN PLEKHF2 SMARCB1
Entrez ID		54820	57541
HPRD ID		14815	18336
Ensembl ID		ENSG00000072864	ENSG00000197024
Uniprot IDs		Q9NXR1 X5DP35 X5DR54	A0A090N7S8 A0A090N8F2 B4DXA9 Q8TD17
PDB IDs
Enriched GO Terms of Interacting Partners?
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