PPIC and ARSA

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		PPIC	ARSA
Description		peptidylprolyl isomerase C	arylsulfatase A
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GO Annotations	Cellular Component	Cytoplasm Extracellular Exosome	Extracellular Region Lysosome Endoplasmic Reticulum Lumen Azurophil Granule Lumen Lysosomal Lumen Extracellular Exosome
	Molecular Function	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding Cyclosporin A Binding Unfolded Protein Binding	Arylsulfatase Activity Cerebroside-sulfatase Activity Calcium Ion Binding Protein Binding Sulfuric Ester Hydrolase Activity
	Biological Process	Protein Peptidyl-prolyl Isomerization Protein Refolding	Glycosphingolipid Metabolic Process Neutrophil Degranulation
Pathways			Glycosphingolipid metabolism The activation of arylsulfatases Neutrophil degranulation
Drugs		L-Proline	N,4-Dihydroxy-N-Oxo-3-(Sulfooxy)Benzenaminium 2-Amino-3-Hydroxy-3-Phosphonooxy-Propionic Acid
Diseases			Metachromatic leukodystrophy (MLD)
GWAS		Aortic root size ( 19584346) Diverticular disease ( 30177863)	Blood metabolite levels ( 24816252) Fibrinogen ( 23969696) Fibrinogen levels ( 28107422) QT interval (ambient particulate matter interaction) ( 28749367) Urinary metabolite levels in chronic kidney disease ( 31959995) vWF and FVIII levels ( 30586737)
Interacting Genes		7 interacting genes: ARSA BANP LGALS3BP SGTA UBAP1 UBQLN1 UBQLN4	8 interacting genes: BMPR2 CETN2 CLEC4G CTSL CYB5R3 GAL3ST1 PPIC TRIP13
Entrez ID		5480	410
HPRD ID		00459	09617
Ensembl ID		ENSG00000168938	ENSG00000100299
Uniprot IDs		P45877	A0A0C4DFZ2 B4DVI5 P15289
PDB IDs		2ESL	1AUK 1E1Z 1E2S 1E33 1E3C 1N2K 1N2L 2AIJ 2AIK 2HI8
Enriched GO Terms of Interacting Partners?
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