KCTD9 and PPP1R16B

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		KCTD9	PPP1R16B
Description		potassium channel tetramerization domain containing 9	protein phosphatase 1 regulatory subunit 16B
Image			No pdb structure
GO Annotations	Cellular Component		Nucleus Plasma Membrane Nuclear Speck Cell Projection Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Identical Protein Binding Protein Self-association Cullin Family Protein Binding	Protein Binding Protein Phosphatase Regulator Activity
	Biological Process	Protein Ubiquitination Intracellular Signal Transduction Protein Homooligomerization	Positive Regulation Of Endothelial Cell Proliferation Regulation Of Phosphatidylinositol 3-kinase Signaling Regulation Of Protein Dephosphorylation Positive Regulation Of Protein Dephosphorylation Negative Regulation Of Protein Dephosphorylation Regulation Of Phosphoprotein Phosphatase Activity Regulation Of Filopodium Assembly Establishment Of Endothelial Barrier Negative Regulation Of Peptidyl-serine Dephosphorylation Positive Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis
Pathways
Drugs
Diseases
GWAS			Alcohol dependence or chronic alcoholic pancreatitis or alcohol-related liver cirrhosis ( 28714907) anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Diverticular disease ( 30177863) Huntington's disease progression ( 28642124) Schizophrenia ( 25056061 29483656 30285260)
Interacting Genes		28 interacting genes: AQP1 CARD9 CBX8 CCDC33 CRADD EHHADH FAM124B GEM GORASP2 KRT40 LONRF1 MAD2L2 MVP PNKD PPP1R16B PPP1R18 PSMA1 PSMB2 RBPMS SDCBP SKP1 SMARCB1 STX11 SYT6 TASOR2 TRIM27 TRIM32 TRIM42	19 interacting genes: CDCA7L CEP55 CEP70 CRX DVL2 GATA1 GOLGA2 IKZF3 KCTD9 NEFL PHC2 PPP1CB RBPMS SF3B4 TADA2A TASOR2 TFIP11 TLE5 ZNF410
Entrez ID		54793	26051
HPRD ID		13772	15168
Ensembl ID		ENSG00000104756	ENSG00000101445
Uniprot IDs		Q7L273	Q96T49
PDB IDs		5BXH
Enriched GO Terms of Interacting Partners?
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