PPIB and PEX19

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		PPIB	PEX19
Description		peptidylprolyl isomerase B	peroxisomal biogenesis factor 19
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Endoplasmic Reticulum Endoplasmic Reticulum Lumen Smooth Endoplasmic Reticulum Focal Adhesion Membrane Protein-containing Complex Endoplasmic Reticulum Chaperone Complex Melanosome Perinuclear Region Of Cytoplasm Extracellular Exosome	Nucleoplasm Cytoplasm Peroxisome Peroxisomal Membrane Cytosol Brush Border Membrane Protein-containing Complex
	Molecular Function	RNA Binding Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding Collagen Binding Cyclosporin A Binding Unfolded Protein Binding RNA Polymerase Binding	Protein Binding Peroxisome Membrane Class-1 Targeting Sequence Binding Protein N-terminus Binding ATPase Binding
	Biological Process	Protein Peptidyl-prolyl Isomerization Positive Regulation Of Multicellular Organism Growth Protein Refolding Positive Regulation By Host Of Viral Process Positive Regulation By Host Of Viral Genome Replication Protein Stabilization Bone Development Chaperone-mediated Protein Folding Regulation Of Post-translational Protein Modification	Protein Targeting To Peroxisome Peroxisome Organization Peroxisome Fission Protein Import Into Peroxisome Membrane Protein Stabilization Transmembrane Transport Chaperone-mediated Protein Folding Chaperone-mediated Protein Transport Establishment Of Protein Localization To Peroxisome Negative Regulation Of Lipid Binding
Pathways		Collagen biosynthesis and modifying enzymes	ABC transporters in lipid homeostasis Class I peroxisomal membrane protein import Class I peroxisomal membrane protein import
Drugs		L-Proline 1,4-Dithiothreitol
Diseases		Osteogenesis imperfecta	Zellweger syndrome spectrum, including: Zellweger syndrome (ZS); Adrenoleukodystrophy, neonatal (NALD); Infantile Refsum disease (IRD)
GWAS
Interacting Genes		19 interacting genes: APOB ATP12A BANP CAMLG DNM2 ESR1 GLP1R H3-4 IRF3 MDM2 PEX19 PRL SGTA SGTB STAT5A TP53 UBQLN1 UBQLN4 VKORC1	32 interacting genes: ABCD1 ABCD2 ABCD3 CDC25A CDKN2A EIF1B F11R FKBP7 GSKIP IL23A IRF3 KIFAP3 MFSD5 OIP5 PEX10 PEX11A PEX11B PEX12 PEX13 PEX14 PEX16 PEX26 PEX3 PMP22 PPIB PXMP4 SLC25A17 SLC34A1 SMAD2 SRPK1 STK3 TMEM54
Entrez ID		5479	5824
HPRD ID		00458	02610
Ensembl ID		ENSG00000166794	ENSG00000162735
Uniprot IDs		P23284	A0A0S2Z497 P40855
PDB IDs		1CYN 3ICH 3ICI	2W85 2WL8 3AJB 3MK4 5LNF
Enriched GO Terms of Interacting Partners?
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