ALKBH4 and MLLT1

Number of citations of the paper that reports this interaction (PubMedID 23145062)
8

Data Source:
BioGRID (two hybrid)

		ALKBH4	MLLT1
Description		alkB homolog 4, lysine demethylase	MLLT1 super elongation complex subunit
Image		No pdb structure
GO Annotations	Cellular Component	Nucleolus Cytoplasm Midbody Contractile Ring	Fibrillar Center Nucleus Nucleoplasm Cytosol Transcription Elongation Factor Complex
	Molecular Function	Actin Binding Protein Binding Oxidoreductase Activity Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen, 2-oxoglutarate As One Donor, And Incorporation Of One Atom Each Of Oxygen Into Both Donors Demethylase Activity Oxidative DNA Demethylase Activity Metal Ion Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding
	Biological Process	Chromatin Organization Protein Demethylation Actomyosin Structure Organization Oxidative DNA Demethylation Cleavage Furrow Ingression Oxidative Demethylation DNA Demethylation Regulation Of Chromatin Organization	Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Transcription Elongation From RNA Polymerase II Promoter Negative Regulation Of Protein Kinase Activity
Pathways			Formation of RNA Pol II elongation complex RNA Polymerase II Pre-transcription Events RNA Polymerase II Transcription Elongation
Drugs
Diseases			Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia)
GWAS		Morning person ( 30696823)	Oppositional defiant disorder dimensions in attention-deficit hyperactivity disorder ( 27021288)
Interacting Genes		12 interacting genes: DTX2 EIF3C EP300 HSF4 MEPCE MLLT1 MLLT3 MTMR6 PSMA6 TES TRAF4 ZFHX3	11 interacting genes: AFF1 AFF4 ALKBH4 ARID1A BMI1 CBX8 H1-5 H3-4 MLLT10 PAF1 WDR5
Entrez ID		54784	4298
HPRD ID		07875	15933
Ensembl ID		ENSG00000160993	ENSG00000130382
Uniprot IDs		Q9NXW9	Q03111
PDB IDs			5J9S 6HPW 6HPX 6HPY 6HPZ 6HQ0 6HT0 6HT1 6T1I 6T1J 6T1L 6T1M 6T1N 6T1O
Enriched GO Terms of Interacting Partners?
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