CTSA and GLB1

Number of citations of the paper that reports this interaction (PubMedID 9501080)
24

Data Source:
HPRD (in vitro)

		CTSA	GLB1
Description		cathepsin A	galactosidase beta 1
Image
GO Annotations	Cellular Component	Extracellular Region Lysosome Endoplasmic Reticulum Membrane Azurophil Granule Lumen Lysosomal Lumen Intracellular Membrane-bounded Organelle Extracellular Exosome Lumenal Side Of Lysosomal Membrane	Extracellular Region Cytoplasm Vacuole Golgi Apparatus Azurophil Granule Lumen Lysosomal Lumen Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Extracellular Exosome Ficolin-1-rich Granule Lumen
	Molecular Function	Carboxypeptidase Activity Serine-type Carboxypeptidase Activity Enzyme Activator Activity	Beta-galactosidase Activity Protein Binding Galactoside Binding Protein Homodimerization Activity
	Biological Process	Proteolysis Glycosphingolipid Metabolic Process Intracellular Protein Transport Regulation Of Protein Stability Positive Regulation Of Catalytic Activity Neutrophil Degranulation Proteolysis Involved In Cellular Protein Catabolic Process Regulation Of Chaperone-mediated Autophagy Negative Regulation Of Chaperone-mediated Autophagy	Glycosaminoglycan Catabolic Process Glycosphingolipid Metabolic Process Galactose Catabolic Process Keratan Sulfate Catabolic Process Neutrophil Degranulation Cellular Carbohydrate Metabolic Process Response To Cortisone Response To Thyroglobulin Triiodothyronine
Pathways		Glycosphingolipid metabolism MHC class II antigen presentation Sialic acid metabolism Defective NEU1 causes sialidosis Neutrophil degranulation	Glycosphingolipid metabolism Keratan sulfate degradation HS-GAG degradation MPS IV - Morquio syndrome B Sialic acid metabolism Defective NEU1 causes sialidosis Neutrophil degranulation
Drugs
Diseases		Galactosialidosis	Galactosialidosis GM1 gangliosidosis Mucopolysaccharidosis type IV (MPS4), including: Morquio syndrome A (MPS4A); Morquio syndrome B (MPS4B)
GWAS			Allergic disease (asthma, hay fever or eczema) ( 29083406) Asthma ( 31361310 30929738 31619474) Asthma (adult onset) ( 30929738) Asthma (childhood onset) ( 31036433 30929738) Atopic dermatitis ( 23042114) Celiac disease ( 22057235) Eosinophil counts ( 29403010 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 27863252) Hepatocellular carcinoma ( 21105107) Medication use (adrenergics, inhalants) ( 31015401) Medication use (glucocorticoids) ( 31015401) Neutrophil percentage of granulocytes ( 27863252) Sum eosinophil basophil counts ( 27863252)
Interacting Genes		4 interacting genes: GLB1 LAMP2 LMNA NEU1	7 interacting genes: CSNK2B CTSA DNAJB1 FOS NEU1 PLK1 TK1
Entrez ID		5476	2720
HPRD ID		02020	01975
Ensembl ID		ENSG00000064601	ENSG00000170266
Uniprot IDs		B4E324 P10619 X6R5C5 X6R8A1	B7Z6Q5 P16278
PDB IDs		1IVY 3BP4 3BP7 3BXN 4AZ0 4AZ3 4CI9 4CIA 4CIB 4MWS 4MWT	3THC 3THD 3WEZ 3WF0 3WF1 3WF2 3WF3 3WF4
Enriched GO Terms of Interacting Partners?
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