ARL15 and UBR1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ARL15	UBR1
Description		ADP ribosylation factor like GTPase 15	ubiquitin protein ligase E3 component n-recognin 1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Exosome	Ubiquitin Ligase Complex Proteasome Complex Cytoplasm Cytosol
	Molecular Function	Molecular_function GTP Binding	Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Activity Leucine Binding
	Biological Process	Biological_process	Protein Ubiquitination Negative Regulation Of TOR Signaling Cellular Response To Leucine Ubiquitin-dependent Protein Catabolic Process Via The N-end Rule Pathway
Pathways			Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases			Johanson-Blizzard syndrome
GWAS		Adiponectin levels ( 20011104 22479202) Age-related cognitive decline (language) (slope of z-scores) ( 30954325) Alcohol dependence (age at onset) ( 24962325) Alcoholic chronic pancreatitis ( 28754779) Brown vs. black hair color ( 30531825) Coffee consumption ( 31046077) Coronary artery disease ( 29212778) Emphysema imaging phenotypes ( 26030696) Estimated glomerular filtration rate ( 31152163 31015462 31451708 30604766) Estimated glomerular filtration rate in non-diabetics ( 31451708) FEV1 ( 30804560) Glomerular filtration rate (creatinine) ( 28452372 26831199) Glycine levels ( 30837465) HDL cholesterol ( 24097068 30275531 20686565) HDL cholesterol levels ( 28334899) High light scatter reticulocyte count ( 27863252) Lung function (FVC) ( 28166213 30804560) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Metabolite levels ( 31628463) Monobrow ( 27182965) Night sleep phenotypes ( 27126917) Pulse pressure ( 27841878) Reticulocyte count ( 27863252) Reticulocyte fraction of red cells ( 27863252) Rheumatoid arthritis ( 23918589) Right lateral prefrontal cortical growth ( 29682794) Systolic blood pressure ( 27841878) Systolic blood pressure (dietary potassium intake interaction) ( 29212900) Triglycerides ( 30275531) Type 2 diabetes ( 24509480 30054458 29358691 30297969 30718926 28869590) Urinary albumin excretion ( 30220432) Urinary albumin-to-creatinine ratio ( 31630189 31511532) Urinary magnesium excretion ( 31993563) Urinary magnesium-to-creatinine ratio ( 29093028) Waist circumference adjusted for body mass index ( 25673412)	MGMT methylation in smokers ( 26183928) Triglycerides ( 25961943)
Interacting Genes		13 interacting genes: B4GALT3 CCDC90B CRMP1 FUNDC2 GAPDH GRIPAP1 PDE6D PTN RPL8 TFG TUBB2A UBR1 UNC119	26 interacting genes: ANXA3 ARL15 ARL3 ARL4D BCL2L1 BTBD2 CDC42 CDC6 DLEU1 DNAJB11 FOS FTH1 GADD45A GSK3B LAMA4 LAMTOR3 NDUFA4L2 NUDT3 PTPRS SERPINB9 SPRY2 TAC3 TP53I3 UBE2A UBE2B UBE2D2
Entrez ID		54622	197131
HPRD ID		12471	09342
Ensembl ID		ENSG00000185305	ENSG00000159459
Uniprot IDs		Q9NXU5	Q8IWV7
PDB IDs			3NY1 5TDC
Enriched GO Terms of Interacting Partners?
Tagcloud ?
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