POU2F2 and TXNRD1

Number of citations of the paper that reports this interaction (PubMedID 10383413)
10

Data Source:
BioGRID (pull down)

		POU2F2	TXNRD1
Description		POU class 2 homeobox 2	thioredoxin reductase 1
Image
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Cytoplasm Intracellular Membrane-bounded Organelle	Fibrillar Center Cell Nucleoplasm Cytoplasm Mitochondrion Cytosol Extracellular Exosome
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Domain Specific Binding Sequence-specific DNA Binding	Thioredoxin-disulfide Reductase Activity Protein Binding Electron Transfer Activity Protein Disulfide Oxidoreductase Activity Flavin Adenine Dinucleotide Binding
	Biological Process	Mature B Cell Differentiation Immunoglobulin Secretion Involved In Immune Response Transcription By RNA Polymerase II Humoral Immune Response Cell Differentiation SnRNA Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II Cell Maturation	Mesoderm Formation Selenium Compound Metabolic Process Signal Transduction Cell Proliferation Nucleobase-containing Small Molecule Interconversion Regulation Of Lipid Metabolic Process Electron Transport Chain Cellular Response To Oxidative Stress Cell Redox Homeostasis Cellular Oxidant Detoxification
Pathways		RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes	PPARA activates gene expression Metabolism of ingested H2SeO4 and H2SeO3 into H2Se Detoxification of Reactive Oxygen Species Interconversion of nucleotide di- and triphosphates Metabolism of ingested MeSeO2H into MeSeH Uptake and function of diphtheria toxin TP53 Regulates Metabolic Genes
Drugs			Arsenic trioxide Nadph Dihydro-Nicotinamide-Adenine-Dinucleotidephosphate Flavin adenine dinucleotide Spermidine Fotemustine motexafin gadolinium PX-12
Diseases
GWAS		Alcohol consumption (drinks per week) ( 30643258) Chronotype ( 30696823) Prostate cancer ( 29892016) Prostate cancer (advanced) ( 29892016)	Blood protein levels ( 30072576) Emphysema annual change measurement in smokers (percent low attenuation area) ( 31324189) Logical memory (delayed recall) in normal cognition ( 29274321) Toenail selenium levels ( 25343990)
Interacting Genes		14 interacting genes: AR ESR1 GAPDH HMGA1 HMGB2 MNAT1 NR2F1 NR3C1 PGR POU2AF1 RXRA TBP TXNRD1 XRCC6	10 interacting genes: DMRTC2 ESR1 ESR2 GLRX2 POU2F1 POU2F2 PPP1R16A THRA TXNDC17 TXNIP
Entrez ID		5452	7296
HPRD ID		01251	03068
Ensembl ID		ENSG00000028277	ENSG00000198431
Uniprot IDs		B5ME60 H0YLL6 P09086	B7Z2S5 Q16881
PDB IDs		1HDP	1W1C 2CFY 2J3N 2ZZ0 2ZZB 2ZZC 3QFA 3QFB
Enriched GO Terms of Interacting Partners?
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