RHOF and ANKFY1

Number of citations of the paper that reports this interaction (PubMedID 24102721)
7

Data Source:
BioGRID (affinity chromatography technology, two hybrid)

		RHOF	ANKFY1
Description		ras homolog family member F, filopodia associated	ankyrin repeat and FYVE domain containing 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Plasma Membrane Cell Cortex Secretory Granule Membrane Cytoplasmic Vesicle Cell Division Site Intracellular Membrane-bounded Organelle Extracellular Exosome	Lysosomal Membrane Endosome Early Endosome Cytosol Endosome Membrane Membrane Retromer Complex Intracellular Membrane-bounded Organelle Macropinosome Extracellular Exosome
	Molecular Function	GTPase Activity GTP Binding Protein Kinase Binding	Protein Binding Rab GTPase Binding Metal Ion Binding Phosphatidylinositol Phosphate Binding
	Biological Process	Cytokinesis Actin Filament Organization Establishment Or Maintenance Of Cell Polarity Rho Protein Signal Transduction Regulation Of Cell Shape Cell Migration Regulation Of Cell Migration Establishment Or Maintenance Of Actin Cytoskeleton Polarity Regulation Of Actin Cytoskeleton Organization Neutrophil Degranulation Actin Filament Bundle Assembly Regulation Of Small GTPase Mediated Signal Transduction	Endocytosis Endosomal Transport Endosomal Vesicle Fusion Retrograde Transport, Endosome To Golgi Positive Regulation Of Pinocytosis Golgi To Lysosome Transport
Pathways		Rho GTPase cycle Neutrophil degranulation
Drugs
Diseases
GWAS		Mean platelet volume ( 31194788 27863252) Platelet count ( 27863252) Platelet distribution width ( 27863252) Plateletcrit ( 27863252) Reticulocyte fraction of red cells ( 27863252)	Diastolic blood pressure ( 30578418) Functional impairment in major depressive disorder, bipolar disorder and schizophrenia ( 24039173)
Interacting Genes		1 interacting genes: ANKFY1	6 interacting genes: CLK1 EHD1 RAB5A RHOD RHOF SRPK2
Entrez ID		54509	51479
HPRD ID		15246	09717
Ensembl ID		ENSG00000139725	ENSG00000185722
Uniprot IDs		Q9HBH0	B3KPZ0 Q9P2R3
PDB IDs
Enriched GO Terms of Interacting Partners?
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