CCSER2 and OFD1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CCSER2	OFD1
Description		coiled-coil serine rich protein 2	OFD1 centriole and centriolar satellite protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Microtubule Cytoskeleton	Extracellular Region Nucleus Centrosome Centriole Cytosol Cilium Membrane Centriolar Satellite Ciliary Basal Body
	Molecular Function	Microtubule Binding	Protein Binding Identical Protein Binding Alpha-tubulin Binding Gamma-tubulin Binding
	Biological Process	Microtubule Bundle Formation	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Centriole Replication Regulation Of G2/M Transition Of Mitotic Cell Cycle Axoneme Assembly Cilium Assembly Epithelial Cilium Movement Involved In Determination Of Left/right Asymmetry Mitotic Spindle Assembly Ciliary Basal Body-plasma Membrane Docking
Pathways			Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Hedgehog 'off' state Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs
Diseases			Oral-facial-digital syndrome 1 Joubert syndrome
GWAS		Cerebrospinal P-tau181p levels ( 28247064) Disease progression in age-related macular degeneration (adjusted for baseline) ( 29346644)
Interacting Genes		12 interacting genes: APP ATRX CRADD EXOC1 GHITM GTF2H1 KIFAP3 MAP1LC3B OFD1 PSMD11 STX1A TCEA2	8 interacting genes: CCSER2 CEP126 EIF6 GPRASP1 LUC7L2 NME7 RUVBL1 S100A6
Entrez ID		54462	8481
HPRD ID		13832	02162
Ensembl ID		ENSG00000107771	ENSG00000046651
Uniprot IDs		Q9H7U1	A6NF31 E9KL37 O75665
PDB IDs
Enriched GO Terms of Interacting Partners?
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