GNG2 and SMURF2

  • Number of citations of the paper that reports this interaction (PubMedID 15761153)
  • 246
  • Data Source:
  • HPRD (in vivo)

GNG2

SMURF2

Description G protein subunit gamma 2 SMAD specific E3 ubiquitin protein ligase 2
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Chronic obstructive pulmonary disease ( 25584925)
  • Cognitive decline rate in late mild cognitive impairment ( 26252872)
  • Craniofacial microsomia ( 26853712)
  • High density lipoprotein cholesterol levels ( 29403010)
  • Lung cancer (smoking interaction) ( 24658283)
  • Non-melanoma skin cancer ( 23548203)
  • Post bronchodilator FEV1/FVC ratio ( 26634245)
  • Triglyceride levels ( 31170924)
  • Triglyceride levels x loop diuretics use interaction ( 31806883)
Interacting Genes 15 interacting genes: ADRA2A ADRB2 AVPR2 BTK CACNA1H CHRM2 GNB1 GNB3 GNB4 GNB5 MRGPRX1 PGGT1B PLEKHG2 SMURF2 TBXA2R 90 interacting genes: ABRAXAS2 ACBD3 ACOX3 AIMP2 ANAPC5 ARHGAP5 ASH2L AXIN1 BTRC CANX CNKSR2 CUEDC1 DAB2 DAZAP2 DGCR2 EGFR EPHA1 FKBP4 FLNB FUBP1 GNG2 HDGFL3 ING2 IRF3 IRF8 ITGB1BP1 KLF5 LAPTM5 LATS1 LMNA MAVS NEK6 NKIRAS1 NRAS PDE4B PPID PRICKLE1 PRICKLE2 RAB13 RAB14 RAB17 RAB22A RAB25 RAN RAP1B RASD2 RASL12 RHOA RHOD RLIM RNF11 RNF111 RNF2 RNF20 RPS27A RRAS2 RUNX2 RUNX3 SF3A2 SKIL SMAD1 SMAD2 SMAD3 SMAD5 SMAD6 SMAD7 SMAP1 SNCA SNRNP70 SOCS6 SPART SRSF4 TFPI2 TGFBR1 TMEM139 TNPO3 TOP2A TRAF2 TRAF4 TSSK4 TXNIP UBC UBE2D1 UBE2D2 UBE2D3 UBE2L3 USP15 XPO1 YY1 ZBTB44
Entrez ID 54331 64750
HPRD ID 16234 06901
Ensembl ID ENSG00000186469 ENSG00000108854
Uniprot IDs P59768 Q96DE7 Q9HAU4
PDB IDs 4KFM 5HE0 5HE1 5HE2 5HE3 5UKK 5UKL 5UKM 5UZ7 6B3J 6CRK 6D9H 6DDE 6DDF 6E3Y 6EG8 6G79 6GDG 6M8S 6N4B 6NI3 6NIY 6OIJ 6OIK 6OS9 6OSA 6OT0 1ZVD 2DJY 2JQZ 2KXQ 2LTZ 6FX4
Enriched GO Terms of Interacting Partners?
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