PLP1 and BCL2L13

Number of citations of the paper that reports this interaction (PubMedID 26871637)
108

Data Source:
BioGRID (two hybrid)

		PLP1	BCL2L13
Description		proteolipid protein 1	BCL2 like 13
Image
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Myelin Sheath Synapse	Nucleus Mitochondrion Integral Component Of Membrane Mitochondrial Membrane
	Molecular Function	Structural Molecule Activity Protein Binding Structural Constituent Of Myelin Sheath	Protein Binding Cysteine-type Endopeptidase Activator Activity Involved In Apoptotic Process
	Biological Process	Inflammatory Response Integrin-mediated Signaling Pathway Chemical Synaptic Transmission Axon Ensheathment Glial Cell Differentiation Positive Regulation Of Gene Expression Astrocyte Development Substantia Nigra Development Central Nervous System Myelination Neuron Projection Development Myelination Long-chain Fatty Acid Biosynthetic Process Axon Development	Apoptotic Process Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Pathways
Drugs
Diseases		Hereditary spastic paraplegia (SPG) Hypomyelinating leukodystrophy (HLD); Pelizaeus-Merzbacher disease (PMD)
GWAS			Baseline cortisol levels in response to low dose short synacthen test in corticosteroid treated asthma ( 29551627) Granulocyte count ( 27863252) Interleukin-10 levels ( 22205395) Myeloid white cell count ( 27863252) Neutrophil count ( 27863252) Sum neutrophil eosinophil counts ( 27863252)
Interacting Genes		13 interacting genes: AKT1 BCL2L13 CALR CANX CLN8 CREB3 CREB3L1 GLA ITGAV LMNA MAG MBP PTPRN	15 interacting genes: APP BET1 GABARAPL2 IL17RA MTNR1B NINJ2 PLLP PLN PLP1 TMEM128 TMEM86B TMUB2 UPK1B VAMP3 VAMP4
Entrez ID		5354	23786
HPRD ID		02321	09822
Ensembl ID		ENSG00000123560	ENSG00000099968
Uniprot IDs		A0A0S2Z4D4 A8K9L3 B4DI30 P60201	A0A087WTL4 A0A087WW80 A0A087WX97 A0A0A0MR90 A8K5Y4 B2RB43 B7Z238 B7Z737 E9PDD6 F6VJB4 Q86T62 Q9BXK5
PDB IDs		2XPG	2IPD
Enriched GO Terms of Interacting Partners?
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