PLCD1 and RALA

Number of citations of the paper that reports this interaction (PubMedID 15817490)
19

Data Source:
BioGRID (pull down)
HPRD (two hybrid, in vitro)

		PLCD1	RALA
Description		phospholipase C delta 1	RAS like proto-oncogene A
Image		No pdb structure
GO Annotations	Cellular Component	Cell Cytoplasm Cytosol Plasma Membrane Extracellular Exosome	Plasma Membrane Focal Adhesion Cell Surface Endocytic Vesicle Cytoplasmic Vesicle Membrane Cleavage Furrow Extracellular Exosome Flemming Body
	Molecular Function	Phosphatidylinositol Phospholipase C Activity Calcium Ion Binding Phosphatidylinositol-4,5-bisphosphate Binding GTPase Activating Protein Binding	GTPase Activity Protein Binding GTP Binding Myosin Binding GDP Binding Ubiquitin Protein Ligase Binding Edg-2 Lysophosphatidic Acid Receptor Binding ATPase Binding
	Biological Process	Angiogenesis Phospholipid Metabolic Process Lipid Catabolic Process Inositol Trisphosphate Biosynthetic Process Regulation Of Cell Proliferation Inositol Phosphate Metabolic Process Phosphatidylinositol-mediated Signaling Release Of Sequestered Calcium Ion Into Cytosol Labyrinthine Layer Blood Vessel Development	Neural Tube Closure Exocytosis Chemotaxis Cell Cycle Signal Transduction Ras Protein Signal Transduction Regulation Of Exocytosis Actin Cytoskeleton Reorganization Interleukin-12-mediated Signaling Pathway Cell Division Positive Regulation Of Filopodium Assembly Membrane Raft Localization Membrane Organization
Pathways		Synthesis of IP3 and IP4 in the cytosol	Translocation of SLC2A4 (GLUT4) to the plasma membrane p38MAPK events Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
Drugs		1D-myo-inositol 1,4,5-trisphosphate Inositol 2,4,5-trisphosphate	Guanosine-5'-Diphosphate
Diseases
GWAS
Interacting Genes		9 interacting genes: APP CALM1 GAP43 KPNB1 PAXIP1 RALA RALB TGM2 USP54	36 interacting genes: ACTB AKAP10 ARF1 C1QC CALM1 CNKSR2 CTCF EXOC1 EXOC2 EXOC3 EXOC4 EXOC5 EXOC6B EXOC7 EXOC8 FLNA GCK GLS2 HOXA2 HSPB1 INHBA LSM2 PIH1D2 PLCD1 PLD1 PPP2R1B RAB34 RAB8B RALBP1 RALGPS1 RASSF5 REPS1 RGL2 RGL4 SMAD4 YBX3
Entrez ID		5333	5898
HPRD ID		09073	01549
Ensembl ID		ENSG00000187091	ENSG00000006451
Uniprot IDs		A0A384MR47 A8K8F9 P51178	P11233
PDB IDs			1UAD 1ZC3 1ZC4 2A78 2A9K 2BOV
Enriched GO Terms of Interacting Partners?
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