PLAT and SLC28A2

		PLAT	SLC28A2
Description		plasminogen activator, tissue type	solute carrier family 28 member 2
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cytoplasm Cell Surface Secretory Granule Apical Part Of Cell Collagen-containing Extracellular Matrix Extracellular Exosome Schaffer Collateral - CA1 Synapse Glutamatergic Synapse	Plasma Membrane Integral Component Of Plasma Membrane Membrane
	Molecular Function	Serine-type Endopeptidase Activity Signaling Receptor Binding Protein Binding Phosphoprotein Binding	Nucleoside Transmembrane Transporter Activity Nucleoside:sodium Symporter Activity Purine Nucleoside Transmembrane Transporter Activity
	Biological Process	Response To Hypoxia Cellular Protein Modification Process Proteolysis Blood Coagulation Smooth Muscle Cell Migration Plasminogen Activation Fibrinolysis Negative Regulation Of Proteolysis Platelet-derived Growth Factor Receptor Signaling Pathway Trans-synaptic Signaling By BDNF, Modulating Synaptic Transmission	Nucleobase-containing Compound Metabolic Process Purine Nucleoside Transmembrane Transport Nucleoside Transmembrane Transport
Pathways		Signaling by PDGF Dissolution of Fibrin Clot	Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane
Drugs		Urokinase Aminocaproic Acid Ibuprofen Iloprost Human C1-esterase inhibitor 5-(DIMETHYLAMINO)-2-NAPHTHALENESULFONIC ACID Dexibuprofen Conestat alfa
Diseases
GWAS		Blood protein levels ( 30072576) Plasma plasminogen activator levels ( 24578379) Systemic lupus erythematosus ( 28714469)	Estimated glomerular filtration rate ( 31015462) Uric acid levels ( 22229870) Urinary metabolite levels in chronic kidney disease ( 31959995)
Interacting Genes		36 interacting genes: ANXA2 APP BAG4 CALR CKAP4 CLEC3B CRABP1 CRTC1 DDHD2 EIF4EBP1 F10 FGA FN1 GML GRIN1 HMGB1 KRT8 LAMA1 LAMA3 LRP1 LRP1B MAPK1 MAPK3 MTDH PDGFC PLAU PLG PPP2CB PVR SART1 SERPINA5 SERPINE1 SERPING1 SERPINI1 SLC28A2 SPARC	2 interacting genes: IDE PLAT
Entrez ID		5327	9153
HPRD ID		01419	07069
Ensembl ID		ENSG00000104368	ENSG00000137860
Uniprot IDs		B4DN26 P00750	O43868 Q2M2A7 Q53H72
PDB IDs		1A5H 1BDA 1PK2 1PML 1RTF 1TPG 1TPK 1TPM 1TPN 5BRR 5ZLZ
Enriched GO Terms of Interacting Partners?
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