PGM1 and HSPB2

Number of citations of the paper that reports this interaction (PubMedID 26465331)
5

Data Source:
BioGRID (two hybrid)

		PGM1	HSPB2
Description		phosphoglucomutase 1	heat shock protein family B (small) member 2
Image
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Cytosol Extracellular Exosome Tertiary Granule Lumen Ficolin-1-rich Granule Lumen	Nucleus Cytoplasm Cytosol
	Molecular Function	Magnesium Ion Binding Phosphoglucomutase Activity Protein Binding	Protein Binding Enzyme Activator Activity
	Biological Process	Glycogen Biosynthetic Process Glycogen Catabolic Process Glucose Metabolic Process Gluconeogenesis Glycolytic Process Galactose Catabolic Process Neutrophil Degranulation	Response To Unfolded Protein Positive Regulation Of Catalytic Activity
Pathways		Glycogen synthesis Defective PGM1 causes PGM1-CDG (CDG1t) Neutrophil degranulation
Drugs		Alpha-D-Glucose 1,6-Bisphosphate Alpha-D-Glucose-1-Phosphate-6-Vanadate
Diseases
GWAS		Alcohol consumption (transferrin glycosylation) ( 21665994) Blood protein levels ( 29875488) Type 1 diabetes ( 19430480)
Interacting Genes		12 interacting genes: APP HSPB2 NLRP3 PAXIP1 PEA15 POT1 S100A1 S100B TERF1 TERF2IP TINF2 USP4	89 interacting genes: A2M ABCC9 ABCD4 ACAA2 ACTA1 ACTB ACTC1 ACTG1 AGAP11 ALDH2 ALDOA ASAH1 ATP5F1A ATP6V1E1 B2M BEX4 BGN C1QA CAPZA2 CKM CLK4 CMYA5 CRYAA CRYAB CRYGC CTSB CTSD CYP1B1 DCTN1 DCTN6 DDIT4 DDX10 DMPK DUSP1 EEF1A1 EIF4A2 ENO1 ENO3 ETFA FHL2 FLNC GAPDH GARS1 HADHB HNRNPD HSPB3 HSPB8 LGALS1 MAPKAPK5 MB MCCC2 MDH1 MLF2 MT-CO1 MT-CO2 MT-CO3 MYBPC3 MYH6 MYOM2 MYOZ2 NARS1 NDUFA13 NDUFA6 NT5DC2 PARVA PGM1 PKP2 PPM1K RPL11 RPL36A RPL36AL RPS11 RPS6KA5 RYR2 SDF2 SDHA SLC2A1 SNCA SNU13 TATDN1 TCAP THEMIS2 THUMPD2 TNNI3 TTN TXNIP UBL5 WDR1 ZNF335
Entrez ID		5236	3316
HPRD ID		01389	03712
Ensembl ID		ENSG00000079739	ENSG00000170276
Uniprot IDs		B4DDQ8 B7Z6C2 P36871	A8KAH6 Q16082
PDB IDs		5EPC 5F9C 5HSH 5JN5 5TR2 5VBI 5VEC 5VG7 5VIN 6BJ0	6F2R
Enriched GO Terms of Interacting Partners?
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