PFKL and TESK1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		PFKL	TESK1
Description		phosphofructokinase, liver type	testis associated actin remodelling kinase 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytosol 6-phosphofructokinase Complex Membrane Secretory Granule Lumen Extracellular Exosome Ficolin-1-rich Granule Lumen	Nucleus Cytoplasm Cytosol Cytoplasmic Vesicle
	Molecular Function	6-phosphofructokinase Activity Protein Binding ATP Binding AMP Binding Kinase Binding Identical Protein Binding Metal Ion Binding Monosaccharide Binding Fructose Binding Fructose-6-phosphate Binding	Protein Serine/threonine Kinase Activity Protein Serine/threonine/tyrosine Kinase Activity Protein Tyrosine Kinase Activity Protein Binding ATP Binding Protein C-terminus Binding Protein Kinase Binding Metal Ion Binding
	Biological Process	Fructose 6-phosphate Metabolic Process Glucose Catabolic Process Glycolytic Process Response To Glucose Fructose 1,6-bisphosphate Metabolic Process Neutrophil Degranulation Negative Regulation Of Insulin Secretion Protein Homotetramerization Canonical Glycolysis	Spermatogenesis Peptidyl-tyrosine Phosphorylation Actin Cytoskeleton Organization Negative Regulation Of Protein Autophosphorylation Regulation Of Protein Localization Positive Regulation Of Stress Fiber Assembly Negative Regulation Of Protein Serine/threonine Kinase Activity
Pathways		Neutrophil degranulation Glycolysis	Regulation of cytoskeletal remodeling and cell spreading by IPP complex components
Drugs
Diseases
GWAS		Rheumatoid arthritis ( 21505073)
Interacting Genes		13 interacting genes: APP ATN1 COPS6 GTPBP3 KRTAP10-7 KRTAP4-12 KRTAP5-9 MYD88 PCNT PFKM PRPF40A TESK1 YWHAQ	8 interacting genes: ABCB4 ARAF CFL1 IL17RA PFKL SPRY4 YWHAB YY1
Entrez ID		5211	7016
HPRD ID		01385	03470
Ensembl ID		ENSG00000141959	ENSG00000107140
Uniprot IDs		P17858 Q7L2M7	Q15569 Q8NFJ4
PDB IDs
Enriched GO Terms of Interacting Partners?
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