UBE2D4 and CADPS2

Number of citations of the paper that reports this interaction (PubMedID 19690564)
57

Data Source:
BioGRID (two hybrid)

		UBE2D4	CADPS2
Description		ubiquitin conjugating enzyme E2 D4 (putative)	calcium dependent secretion activator 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex	Nucleoplasm Cell Junction Cytoplasmic Vesicle Membrane Presynaptic Membrane Intracellular Membrane-bounded Organelle Postsynaptic Membrane Parallel Fiber To Purkinje Cell Synapse Glutamatergic Synapse
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding ATP Binding Ubiquitin Protein Ligase Binding Ubiquitin Conjugating Enzyme Activity	Lipid Binding Metal Ion Binding
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Protein K29-linked Ubiquitination Protein K27-linked Ubiquitination Protein K63-linked Ubiquitination Protein K48-linked Ubiquitination Protein K11-linked Ubiquitination Protein K6-linked Ubiquitination	Exocytosis Cellular Response To Starvation Protein Transport Synaptic Vesicle Priming Positive Regulation Of Exocytosis Dense Core Granule Exocytosis
Pathways		Antigen processing: Ubiquitination & Proteasome degradation
Drugs			Calcium Citrate Calcium Phosphate
Diseases
GWAS			Attention deficit hyperactivity disorder ( 30478444) Brain structure ( 20171287) General risk tolerance (MTAG) ( 30643258) Menarche (age at onset) ( 25231870) Number of sexual partners ( 30643258) Serum sulfate level ( 27412988) Smoking status (ever vs never smokers) ( 30643258) Waist circumference ( 28552196)
Interacting Genes		99 interacting genes: AMFR ARIH2 BFAR BIRC8 CADPS2 CHFR CNOT4 DAZAP2 DTX1 DTX2 DTX3 DTX3L DZIP3 INCA1 ITCH LRSAM1 MAGEA11 MAP3K1 MARCHF3 MDM2 MGRN1 MIB1 MID1 MID2 MKRN2 MKRN3 MUL1 MYBL2 MYLIP OTUB1 PHF7 PJA2 PRKN RBCK1 RCHY1 RFWD3 RING1 RLIM RMND5B RNF10 RNF103 RNF11 RNF111 RNF114 RNF115 RNF125 RNF126 RNF13 RNF130 RNF138 RNF14 RNF150 RNF165 RNF166 RNF167 RNF181 RNF185 RNF2 RNF216 RNF26 RNF31 RNF38 RNF4 RNF43 RNF5 RNF7 SIAH1 STUB1 TOPORS TRAF6 TRAF7 TRIM10 TRIM17 TRIM2 TRIM23 TRIM25 TRIM27 TRIM3 TRIM31 TRIM35 TRIM38 TRIM39 TRIM43 TRIM45 TRIM5 TRIM50 TRIM8 UBA1 UBC UBE4A UBOX5 UBTD1 UFM1 UHRF2 UVSSA XIAP ZNRF1 ZNRF2 ZNRF4	15 interacting genes: BDNF DMD DRD2 MEGF10 SRPK2 TSPOAP1 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E3 UBE2N UBE2U UBE2W
Entrez ID		51619	93664
HPRD ID		14242	12996
Ensembl ID		ENSG00000078967	ENSG00000081803
Uniprot IDs		A0A024RA90 Q9UQL0 Q9Y2X8	B7ZM57 Q86UW7 X5DNG0
PDB IDs
Enriched GO Terms of Interacting Partners?
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